ID V1A_TAV STANDARD; PRT; 993 AA. AC P28931; DT 01-DEC-1992 (Rel. 24, Created) DT 01-DEC-1992 (Rel. 24, Last sequence update) DT 15-JUL-1999 (Rel. 38, Last annotation update) DE 1A PROTEIN [INCLUDES: HELICASE; METHYLTRANSFERASE]. OS Tomato aspermy virus (TAV). OC Viruses; ssRNA positive-strand viruses, no DNA stage; Bromoviridae; OC Cucumovirus. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=V; RX MEDLINE; 91374017. RA Bernal J.J., Moriones E., Garcia-Arenal F.; RT "Evolutionary relationships in the cucumoviruses: nucleotide sequence RT of tomato aspermy virus RNA 1."; RL J. Gen. Virol. 72:2191-2195(1991). CC -!- FUNCTION: MAY BE INVOLVED IN THE REPLICATION OF THE VIRUS. CC CONTAINS AN HELICASE DOMAIN AND A METHYLTRANSFERASE DOMAIN. THE CC METHYLTRANSFERASE DOMAIN IS PROBABLY INVOLVED IN VIRAL RNA CC CAPPING. CC -!- SIMILARITY: TO 1A PROTEIN FROM BMV, CCMV, CMV AND PSV. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; D10044; BAA00936.1; -. DR PIR; JQ1370; P1VXTA. DR INTERPRO; IPR000606; -. DR INTERPRO; IPR002588; -. DR PFAM; PF01443; Viral_helicase1; 1. DR PFAM; PF01660; Vmethyltransf; 1. KW Helicase; ATP-binding; Transferase; Methyltransferase. FT NP_BIND 714 721 ATP (POTENTIAL). SQ SEQUENCE 993 AA; 112062 MW; 516926DD910FF4EA CRC64; MAASAFNIHK LVASHGDKGL LASALVDKLA HEQLEEQVQH QRRGLKVYIR NALDVKDSEI IRDRYGGKYD LHLTQQEQAP HGLAGALRLC ELLDCLDSFP RTGLRQDLVL DFGGSWVTHY LRGHNVHCCS PCLGIRDKMR HTERLMTMRK VIVNDPDTFE SRVPDFCTLP AEDCKVQAHF VISIHGGYDM GFKGLCRAMH AHGTTFLKGT MMFDGAMLFD TEGYLADLKC KWKKIKPRTY ESEDQTPLLS RISDNLTTTI KDHTLIAFDF VDESTLSYVH KWENVKSFLT DQTYSYKGMT YGLERCLIQH GIMTYKIIAV PGTCPPELIR HCIWFTSLKD YVGLKIPVSQ DLVEWKTVRI LISTLRETEE IAMRCYSDKK NWLEQFKVIL GVLSSKSSTI VINGMAMQAG ERIDTSDYHY IGLAILLHTR MKYEQLGRMY DMWNSTFIRK FFASLTRPMR VFLSACVKTL FPTLRPRDEK EFLVKLSTFV TFNEVCQVDL DAEWDVISSA AFTAEMAVED GKRLAEDRKQ KAEAASQIPV DEIPDDTAES SDDTPREADT NQKSEPSSPE LETLSTQTRS PITRLAQRAS SMLEYSAYEA QLHDNAVSNL DRMWCMAGGD KKNNRLESNV KFVFETYHIV DPLVNVHFPT GRWLYRVPEG ISYSVGFNEH GIGPKADGEL YIVNADCVIS NSKCLADTTL QYLAPTGTIS LVDGVAGCGK TTAIKKMFNP ATDVIVTANK KSALDVRQAL FNCTDSKEAT TFVRTADSIL MNDTNEVQRV LVDEVVLLHF GQLCAVMSKL KAVRAICFGD SEQIAFCSRD ASFDMRHSTI IPDETDTADT TFRSPQDVIK VVKCMASKAL KKGTHSKYAS WVSQSKVQRS VSSKAVASVT MVDLTEDRFY ITMTQADKTA LRTRARELNM SNDFIEHRIK TTHESQGVSE DHVTLVRLKT TKCDLFKAFK YCLVAVTRHK KTFRYEHVGK LDGDLIAECL ARV //