ID ARA4_ARATH Reviewed; 214 AA. AC P28187; DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot. DT 01-DEC-1992, sequence version 1. DT 13-OCT-2009, entry version 81. DE RecName: Full=Ras-related protein ARA-4; GN Name=ARA-4; OrderedLocusNames=At2g43130; ORFNames=F14B2.7; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; OC rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RC STRAIN=cv. Columbia, cv. En-1, cv. Estland, cv. Landsberg erecta, and RC cv. Lapalmam; TISSUE=Leaf; RX MEDLINE=92084144; PubMed=1748311; DOI=10.1016/0378-1119(91)90442-E; RA Anai T., Hasegawa K., Watanabe Y., Uchimiya H., Ishizaki R., RA Matsui M.; RT "Isolation and analysis of cDNAs encoding small GTP-binding proteins RT of Arabidopsis thaliana."; RL Gene 108:259-264(1991). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX MEDLINE=20083487; PubMed=10617197; DOI=10.1038/45471; RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., RA Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., RA Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., RA Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., RA Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., RA Venter J.C.; RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis RT thaliana."; RL Nature 402:761-768(1999). CC -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic CC side (Potential). CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; D01026; BAA00831.1; -; mRNA. DR EMBL; AC004450; AAC64302.1; -; Genomic_DNA. DR IPI; IPI00531444; -. DR PIR; JS0641; JS0641. DR RefSeq; NP_181842.1; -. DR UniGene; At.259; -. DR HSSP; P21181; 1AM4. DR STRING; P28187; -. DR PRIDE; P28187; -. DR GeneID; 818915; -. DR GenomeReviews; CT485783_GR; AT2G43130. DR KEGG; ath:AT2G43130; -. DR TAIR; At2g43130; -. DR ArrayExpress; P28187; -. DR Genevestigator; P28187; -. DR GermOnline; AT2G43130; Arabidopsis thaliana. DR GO; GO:0005795; C:Golgi stack; IDA:TAIR. DR GO; GO:0005798; C:Golgi-associated vesicle; IDA:TAIR. DR GO; GO:0009898; C:internal side of plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005802; C:trans-Golgi network; IDA:TAIR. DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW. DR GO; GO:0048219; P:inter-Golgi cisterna vesicle-mediated trans...; TAS:TAIR. DR GO; GO:0015031; P:protein transport; IEA:InterPro. DR GO; GO:0009408; P:response to heat; IEP:TAIR. DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. DR InterPro; IPR003579; GTPase_Rab. DR InterPro; IPR015595; Rab11. DR InterPro; IPR013753; Ras. DR InterPro; IPR001806; Ras_GTPase. DR InterPro; IPR005225; Small_GTP_bd. DR PANTHER; PTHR11708:SF213; Rab11; 1. DR Pfam; PF00071; Ras; 1. DR PRINTS; PR00449; RASTRNSFRMNG. DR SMART; SM00175; RAB; 1. DR TIGRFAMs; TIGR00231; small_GTP; 1. DR PROSITE; PS51419; RAB; 1. PE 2: Evidence at transcript level; KW Cell membrane; Complete proteome; GTP-binding; Lipoprotein; Membrane; KW Nucleotide-binding; Prenylation. FT CHAIN 1 214 Ras-related protein ARA-4. FT /FTId=PRO_0000121291. FT NP_BIND 19 26 GTP (By similarity). FT NP_BIND 67 71 GTP (By similarity). FT NP_BIND 125 128 GTP (By similarity). FT MOTIF 41 49 Effector region (By similarity). FT LIPID 211 211 S-geranylgeranyl cysteine (By FT similarity). FT LIPID 212 212 S-geranylgeranyl cysteine (By FT similarity). SQ SEQUENCE 214 AA; 23981 MW; B5C11E754C14535C CRC64; MSDDDERGEE YLFKIVIIGD SAVGKSNLLT RYARNEFNPN SKATIGVEFQ TQSMLIDGKE VKAQIWDTAG QERFRAVTSA YYRGAVGALV VYDITRSSTF ENVGRWLDEL NTHSDTTVAK MLIGNKCDLE SIRAVSVEEG KSLAESEGLF FMETSALDST NVKTAFEMVI REIYSNISRK QLNSDSYKEE LTVNRVSLVK NENEGTKTFS CCSR //