ID DCMB_MOOTH STANDARD; PRT; 674 AA. AC P27989; DT 01-AUG-1992 (Rel. 23, Created) DT 01-AUG-1992 (Rel. 23, Last sequence update) DT 15-JUL-1999 (Rel. 38, Last annotation update) DE Carbon monoxide dehydrogenase beta subunit (EC 1.2.99.2) (CODH). OS Moorella thermoacetica (Clostridium thermoaceticum). OC Bacteria; Firmicutes; Clostridia; Thermoanaerobacteriales; OC Thermoanaerobacteriaceae; Moorella group; Moorella. OX NCBI_TaxID=1525; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=92084676; PubMed=1748656; RA Morton T.A., Runquist J.A., Ragsdale S.W., Shanmugasundaram T., RA Wood H.G., Ljungdahl L.G.; RT "The primary structure of the subunits of carbon monoxide RT dehydrogenase/acetyl-CoA synthase from Clostridium thermoaceticum."; RL J. Biol. Chem. 266:23824-23828(1991). CC -!- FUNCTION: CATALYZES THE INTERCONVERSION OF CO AND CO2 AND THE CC SYNTHESIS OF ACETYL-COENZYME A FROM THE METHYLATED CORRINOID/IRON CC SULFUR PROTEIN, CO, AND COENZYME A. CC -!- CATALYTIC ACTIVITY: CO + H(2)O + acceptor = CO(2) + reduced CC acceptor. CC -!- COFACTOR: NICKEL. CC -!- SUBUNIT: TETRAMER OF TWO ALPHA AND TWO BETA CHAINS. CC -!- SIMILARITY: TO R.RUBRUM CARBON MONOXIDE DEHYDROGENASE. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M62727; AAA23228.1; -. DR PIR; A41670; A41670. DR InterPro; IPR004137; Prismane. DR Pfam; PF03063; Prismane; 1. KW Oxidoreductase; Nickel; Iron-sulfur; Electron transport. FT METAL 68 68 IRON-SULFUR (BY SIMILARITY). FT METAL 71 71 IRON-SULFUR (BY SIMILARITY). FT METAL 90 90 IRON-SULFUR (BY SIMILARITY). SQ SEQUENCE 674 AA; 72924 MW; 54BA3D816C25F9FC CRC64; MPRFRDLSHN CRPSEAPRVM EPKNRDRTVD PAVLEMLVKS KDDKVITAFD RFVAQQPQCK IGYEGICCRF CMAGPCRIKA TDGPGSRGIC GASAWTIVAR NVGLMILTGA AAHCEHGNHI AHALVEMAEG KAPDYSVKDE AKLKEVCRRV GIEVEGKSVL ELAQEVGEKA LEDFRRLKGE GEATWLMTTI NEGRKEKFRT HNVVPFGIHA SISELVNQAH MGMDNDPVNL VFSAIRVALA DYTGEHIATD FSDILFGTPQ PVVSEANMGV LDPDQVNFVL HGHNPLLSEI IVQAAREMEG EAKAAGAKGI NLVGICCTGN EVLMRQGIPL VTSFASQELA ICTGAIDAMC VDVQCIMPSI SAVAECYHTR IITTADNAKI PGAYHIDYQT ATAIESAKTA IRMAIEAFKE RKESNRPVYI PQIKNRVVAG WSLEALTKLL ATQNAQNPIR VLNQAILDGE LAGVALICGC NNLKGFQDNS HLTVMKELLK NNVFVVATGC SAQAAGKLGL LDPANVETYC GDGLKGFLKR LGEGANIEIG LPPVFHMGSC VDNSRAVDLL MAMANDLGVD TPKVPFVASA PEAMSGKAAA IGTWWVSLGV PTHVGTMPPV EGSDLIYSIL TQIASDVYGG YFIFEMDPQV AARKILDALE YRTWKLGVHK EVAERYETKL CQGY //