ID VE6_HPV58 Reviewed; 149 AA. AC P26555; DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot. DT 01-AUG-1992, sequence version 1. DT 31-OCT-2006, entry version 32. DE Protein E6. GN Name=E6; OS Human papillomavirus type 58. OC Viruses; dsDNA viruses, no RNA stage; Papillomaviridae; OC Alphapapillomavirus. OX NCBI_TaxID=10598; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX MEDLINE=92024102; PubMed=1656594; RA Kirii Y., Iwamoto S., Matsukura T.; RT "Human papillomavirus type 58 DNA sequence."; RL Virology 185:424-427(1991). CC -!- FUNCTION: Transcriptional transactivator. Binds double stranded CC DNA (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus; nuclear matrix (By similarity). CC -!- SIMILARITY: Belongs to the papillomaviruses E6 protein family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; D90400; BAA31845.1; -; Genomic_DNA. DR PIR; E36779; W6WL58. DR InterPro; IPR001334; E6. DR InterPro; IPR009083; TFIIA_helical. DR Pfam; PF00518; E6; 1. KW Activator; DNA-binding; Early protein; Metal-binding; Nuclear protein; KW Transcription; Transcription regulation; Zinc; Zinc-finger. FT CHAIN 1 149 Protein E6. FT /FTId=PRO_0000133374. FT ZN_FING 30 66 Potential. FT ZN_FING 103 139 Potential. SQ SEQUENCE 149 AA; 17794 MW; 79B3DCC95831B158 CRC64; MFQDAEEKPR TLHDLCQALE TSVHEIELKC VECKKTLQRS EVYDFVFADL RIVYRDGNPF AVCKVCLRLL SKISEYRHYN YSLYGDTLEQ TLKKCLNEIL IRCIICQRPL CPQEKKRHVD LNKRFHNISG RWTGRCAVCW RPRRRQTQV //