ID P43_XENLA Reviewed; 365 AA. AC P25456; DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-1992, sequence version 1. DT 02-JUN-2021, entry version 92. DE RecName: Full=P43 5S RNA-binding protein; DE AltName: Full=42S P43; DE AltName: Full=Thesaurin-B; OS Xenopus laevis (African clawed frog). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus. OX NCBI_TaxID=8355; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RX PubMed=2331751; DOI=10.1016/0092-8674(90)90809-s; RA Joho K.E., Darby M.K., Crawford E.T., Brown D.D.; RT "A finger protein structurally similar to TFIIIA that binds exclusively to RT 5S RNA in Xenopus."; RL Cell 61:293-300(1990). CC -!- FUNCTION: p43 is a 5S RNA binding protein which is a major constituent CC of oocytes and comprises part of a 42S ribonucleoprotein storage CC particle. CC -!- SUBUNIT: The 42S RNP particle comprises four subunits each of which CC contains one molecule of 5S RNA, three molecules of tRNA, two molecules CC of p50 (EF1-alpha) and one molecule of the 5S RNA binding protein 43. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M32473; AAA49714.1; -; mRNA. DR PIR; C34895; C34895. DR RefSeq; NP_001081272.1; NM_001087803.1. DR SMR; P25456; -. DR PRIDE; P25456; -. DR GeneID; 397745; -. DR KEGG; xla:397745; -. DR CTD; 397745; -. DR Xenbase; XB-GENE-6252610; 42sp43.L. DR OrthoDB; 1318335at2759; -. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW. DR InterPro; IPR036236; Znf_C2H2_sf. DR InterPro; IPR013087; Znf_C2H2_type. DR Pfam; PF00096; zf-C2H2; 4. DR SMART; SM00355; ZnF_C2H2; 9. DR SUPFAM; SSF57667; SSF57667; 4. DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7. DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7. PE 2: Evidence at transcript level; KW Metal-binding; Repeat; RNA-binding; Zinc; Zinc-finger. FT CHAIN 1..365 FT /note="P43 5S RNA-binding protein" FT /id="PRO_0000047089" FT ZN_FING 15..39 FT /note="C2H2-type 1" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042" FT ZN_FING 45..69 FT /note="C2H2-type 2" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042" FT ZN_FING 75..100 FT /note="C2H2-type 3" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042" FT ZN_FING 106..130 FT /note="C2H2-type 4" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042" FT ZN_FING 136..160 FT /note="C2H2-type 5" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042" FT ZN_FING 163..187 FT /note="C2H2-type 6" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042" FT ZN_FING 191..213 FT /note="C2H2-type 7" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042" FT ZN_FING 220..245 FT /note="C2H2-type 8" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042" FT ZN_FING 251..275 FT /note="C2H2-type 9" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042" SQ SEQUENCE 365 AA; 41694 MW; 2EB5BE66D7192995 CRC64; MKNVGETGPG KCQLLRCPAA GCKAFYRKEG KLQDHMAGHS EQKPWKCGIK DCDKVFARKR QILKHVKRHL ALKKLSCPTA GCKMTFSTKK SLSRHKLYKH GEAVPLKCFV PGCKRSFRKK RALRRHLSVH SNEPLSVCDV PGCSWKSSSV AKLVAHQKRH RGYRCSYEGC QTVSPTWTAL QTHVKKHPLE LQCAACKKPF KKASALRRHK ATHAKKPLQL PCPRQDCDKT FSSVFNLTHH VRKLHLCLQT HRCPHSGCTR SFAMRESLLR HLVVHDPERK KLKLKFVRGP SKFLGRGTRC RTPVVEEDLS HLFSRKLLFH FKTRLETNLS GLFNERQLRE PAEPEVNLSG LFQRPQGRAK AEKSA //