ID LASR_PSEAE STANDARD; PRT; 239 AA. AC P25084; Q51475; Q51476; DT 01-MAY-1992 (REL. 22, CREATED) DT 01-MAY-1992 (REL. 22, LAST SEQUENCE UPDATE) DT 01-NOV-1997 (REL. 35, LAST ANNOTATION UPDATE) DE LASR REGULATORY PROTEIN. GN LASR. OS PSEUDOMONAS AERUGINOSA. OC PROKARYOTA; GRACILICUTES; SCOTOBACTERIA; AEROBIC RODS AND COCCI; OC PSEUDOMONADACEAE. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=PAO1; RX MEDLINE; 91210193. RA GAMBELLO M.J., IGLEWSKI B.H.; RL J. BACTERIOL. 173:3000-3009(1991). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=PA103, AND IFO 3455; RX MEDLINE; 95023115. RA FUKUSHIMA J., ISHIWATA T., KURATA M., YOU Z., OKUDA K.; RL NUCLEIC ACIDS RES. 22:3706-3707(1994). CC -!- FUNCTION: TRANSCRIPTIONAL ACTIVATOR OF ELASTASE STRUCTURAL GENE CC (LASB). BINDS TO THE PAI AUTOINDUCER. CC -!- LASR IN STRAIN PA103 IS NOT ACTIVE, THIS IS PROBABLY DUE TO THE CC CHANGE IN POSITION 180 OF THE SEQUENCE. CC -!- SIMILARITY: BELONGS TO THE LUXR/UHPA FAMILY OF TRANSCRIPTIONAL CC REGULATORS; AUTOINDUCER REGULATED SUBFAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M59425; G151326; -. DR EMBL; D30813; G541659; -. DR EMBL; D30812; G541657; -. DR PIR; A43660; A43660. DR PROSITE; PS00622; HTH_LUXR_FAMILY; 1. KW TRANSCRIPTION REGULATION; DNA-BINDING; ACTIVATOR; KW AUTOINDUCER INDUCTION. FT DNA_BIND 194 213 H-T-H MOTIF (BY SIMILARITY). FT VARIANT 144 144 M -> I (IN STRAINS IFO 3455 AND PA103). FT VARIANT 180 180 R -> W (IN STRAIN PA103). SQ SEQUENCE 239 AA; 26618 MW; CC6B1BDD CRC32; MALVDGFLEL ERSSGKLEWS AILQKMASDL GFSKILFGLL PKDSQDYENA FIVGNYPAAW REHYDRAGYA RVDPTVSHCT QSVLPIFWEP SIYQTRKQHE FFEEASAAGL VYGLTMPLHG ARGELGALSL SVEAENRAEA NRFMESVLPT LWMLKDYALQ SGAGLAFEHP VSKPVVLTSR EKEVLQWCAI GKTSWEISVI CNCSEANVNF HMGNIRRKFG VTSRRVAAIM AVNLGLITL //