ID CIK0_MOUSE STANDARD; PRT; 129 AA. AC P23299; DT 01-NOV-1991 (REL. 20, CREATED) DT 01-NOV-1991 (REL. 20, LAST SEQUENCE UPDATE) DT 01-NOV-1991 (REL. 20, LAST ANNOTATION UPDATE) DE ISK SLOW VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN. OS MUS MUSCULUS (MOUSE). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA; OC EUTHERIA; RODENTIA. RN [1] RP SEQUENCE FROM N.A. RC TISSUE=HEART; RM 92007723 RA HONORE E., ATTALI B., ROMEY G., HEURTEAUX C., RICARD P., LESAGE F., RA LAZDUNSKI M., BARHANIN J.; RL EMBO J. 10:2805-2811(1991). CC -!- FUNCTION: THIS MEMBRANE PROTEIN INDUCES SELECTIVE POTASSIUM CC PERMEATION BY MEMBRANE DEPOLARIZATION. IT PER SE ACTS AS A CC DISCRETE K(+)-CONDUCING ION CHANNEL, OR ALTERNATIVELY, IT MAY CC SUBSERVE AS A MODULATORY PROTEIN THAT ACTIVATES ENDOGENOUS K(+) CC CHANNELS. CC -!- SIMILARITY: WITH THE HUMAN AND RAT COUNTERPARTS. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; S17307; S17307. KW IONIC CHANNEL; TRANSMEMBRANE; ION TRANSPORT; VOLTAGE-GATED CHANNEL; KW GLYCOPROTEIN. FT TRANSMEM 44 66 POTENTIAL. FT CARBOHYD 5 5 POTENTIAL. FT CARBOHYD 26 26 POTENTIAL. SQ SEQUENCE 129 AA; 14578 MW; 86046 CN; MSLPNSTTVL PFLARLWQET AEQGGNVSGL ARKSQLRDDS KLEALYILMV LGFFGFFTLG IMLSYIRSKK LEHSHDPFNV YIESDAWQEK GKAVFQARVL ESFRACYVIE NQAAVEQPAT HLPELKPLS //