ID CHL1_YEAST STANDARD; PRT; 861 AA. AC P22516; DT 01-AUG-1991 (Rel. 19, Created) DT 01-AUG-1991 (Rel. 19, Last sequence update) DT 01-OCT-1996 (Rel. 34, Last annotation update) DE CHL1 PROTEIN. GN CHL1 OR CTF1 OR YPL008W OR YP8132.05. OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Ascomycota; Saccharomycetes; Saccharomycetales; OC Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=91092258; PubMed=2265610; RA Gerring S.L., Spencer F., Hieter P.; RT "The CHL 1 (CTF 1) gene product of Saccharomyces cerevisiae is RT important for chromosome transmission and normal cell cycle RT progression in G2/M."; RL EMBO J. 9:4347-4358(1990). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=S288C / AB972; RA Badcock K., Churcher C., Walsh S.V., Barrell B.G., Rajandream M.A.; RL Submitted (FEB-1995) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: IMPORTANT FOR CHROMOSOME TRANSMISSION AND NORMAL CELL CC CYCLE PROGRESSION IN G(2)/M. COULD BE AN ATP-DEPENDENT DNA-BINDING CC HELICASE. CC -!- SIMILARITY: BELONGS TO THE RAD3/XPD SUBFAMILY OF HELICASES. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U33335; AAB68097.1; -. DR EMBL; X56584; CAA39922.1; -. DR EMBL; Z48483; CAA88378.1; -. DR EMBL; Z71255; CAA95033.1; -. DR PIR; S12499; S12499. DR SGD; S0005929; CHL1. DR INTERPRO; IPR002464; -. DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1. KW Cell cycle; Helicase; ATP-binding; DNA-binding. FT NP_BIND 42 49 ATP (BY SIMILARITY). FT SITE 393 396 DEAH BOX. SQ SEQUENCE 861 AA; 98805 MW; 15D0CC397A77F8F2 CRC64; MDKKEYSETF YHPYKPYDIQ VQLMETVYRV LSEGKKIAIL ESPTGTGKTL SLICATMTWL RMNKADIFTR METNIKTNED DSENLSDDEP DWVIDTYRKS VLQEKVDLLN DYEKHLNEIN TTSCKQLKTM CDLDKEHGRY KSVDPLRKKR KGARHLDVSL EEQDFIPRPY ESDSENNDTS KSTRGGRISD KDYKLSELNS QIITLLDKID GKVSRDPNNG DRFDVTNQNP VKIYYASRTY SQLGQFTSQL RLPSFPSSFR DKVPDEKVKY LPLASKKQLC INPKVMKWKT LEAINDACAD LRHSKEGCIF YQNTNEWRHC PDTLALRDMI FSEIQDIEDL VPLGKSLGIC PYYASREALP IAEVVTLPYQ YLLSESTRSS LQINLENSIV IIDEAHNLIE TINSIYSSQI SLEDLKNCHK GIVTYFNKFK SRLNPGNRVN LLKLNSLLMT LIQFIVKNFK KIGQEIDPND MFTGSNIDTL NIHKLLRYIK VSKIAYKIDT YNQALKEEES SKNENPIKET HKKSVSSQPL LFKVSQFLYC LTNLTSEGQF FFEKNYSIKY MLLEPSKPFE SILNQAKCVV LAGGTMEPMS EFLSNLLPEV PSEDITTLSC NHVIPKENLQ TYITNQPELE FTFEKRMSPS LVNNHLFQFF VDLSKAVPKK GGIVAFFPSY QYLAHVIQCW KQNDRFATLN NVRKIFYEAK DGDDILSGYS DSVAEGRGSL LLAIVGGKLS EGINFQDDLC RAVVMVGLPF PNIFSGELIV KRKHLAAKIM KSGGTEEEAS RATKEFMENI CMKAVNQSVG RAIRHANDYA NIYLLDVRYN RPNFRKKLSR WVQDSINSEH TTHQVISSTR KFFSMRSLNS R //