ID HME2_HUMAN STANDARD; PRT; 332 AA. AC P19622; DT 01-FEB-1991 (REL. 17, CREATED) DT 01-FEB-1994 (REL. 28, LAST SEQUENCE UPDATE) DT 01-FEB-1994 (REL. 28, LAST ANNOTATION UPDATE) DE HOMEOBOX PROTEIN ENGRAILED-2 (HU-EN-2). GN EN2. OS HOMO SAPIENS (HUMAN). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA; OC EUTHERIA; PRIMATES. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 93185339. RA LOGAN C., HANKS M.C., NOBLE-TOPHAM S., NALLAINATHAN D., RA PROVART N.J., JOYNER A.L.; RL DEV. GENET. 13:345-358(1992). RN [2] RP SEQUENCE OF 229-332 FROM N.A. RX MEDLINE; 89233109. RA POOLE S.J., LAW M.L., KAO F.T., LAU Y.F.; RL GENOMICS 4:225-231(1989). CC -!- SUBCELLULAR LOCATION: NUCLEAR. CC -!- SIMILARITY: STRONG WITH OTHER "ENGRAILED" HOMEOBOX PROTEINS. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L12700; G553280; -. DR EMBL; L12701; G291986; -. DR PIR; A30141; A30141. DR HSSP; P02836; 1ENH. DR TRANSFAC; T02019; -. DR MIM; 131310; -. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS00033; ENGRAILED; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. KW HOMEOBOX; DNA-BINDING; DEVELOPMENTAL PROTEIN; NUCLEAR PROTEIN. FT DNA_BIND 243 302 HOMEOBOX. SQ SEQUENCE 332 AA; 34153 MW; 565F44D0 CRC32; MEENDPKPGE AAAAVEGQRQ PESSPGGGSG GGGGSSPGEA DTGRRRALML PAVLQAPGNH QHPHRITNFF IDNILRPEFG RRKDAGTCCA GAGGGRGGGA GGEGGASGAE GGGGAGGSEQ LLGSGSREPR QNPPCAPGAG GPLPAAGSDS PGDGEGGSKT LSLHGGAKKG GDPGGPLDGS LKARGLGGGD LSVSSDSDSS QAGANLGAQP MLWPAWVYCT RYSDRPSSPR SRKPKKKNPN KEDKRPRTAF TAEQLQRLKA EFQTNRYLTE QRRQSLAQEL SLNESQIKIW FQNKRAKIKK ATGNKNTLAV HLMAQGLYNH STTAKEGKSD SE //