ID COLY$YERPE STANDARD; PRT; 312 AA. AC P17811; DT 01-AUG-1990 (REL. 15, CREATED) DT 01-AUG-1990 (REL. 15, LAST SEQUENCE UPDATE) DT 01-AUG-1990 (REL. 15, LAST ANNOTATION UPDATE) DE COAGULASE/FIBRINOLYSIN PRECURSOR (GENE NAME: PLA). OS YERSINIA PESTIS. OG PLASMID PKYP1. OC PROKARYOTA; GRACILICUTES; SCOTOBACTERIA; FACULTATIVELY ANAEROBIC RODS; OC ENTEROBACTERIACEAE. RN [1] (STRAIN EV76-6, SEQUENCE FROM N.A.) RA MCDONOUGH K.A., FALKOW S.; RL MOL. MICROBIOL. 3:767-775(1989). CC -!- DISEASE: COAGULASE/FIBRINOLYSIN SEEMS TO PLAY AN ESSENTIAL ROLE CC IN PLAGUE TRANSMISSION BY MEDIATING FLEA BLOCKAGE IN A CC TEMPERATURE-DEPENDENT FASHION. FIBRINOLYTIC ACTIVITY PREVAILS CC AT 37 C WHEREAS COAGULASE EXPRESSION PREDOMINATES AT LOWER CC TEMPERATURES (<30 C). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X15136; YPPLA. KW SIGNAL; PLASMID. FT SIGNAL 1 20 POTENTIAL. FT CHAIN 21 312 COAGULASE/FIBRINOLYSIN. SQ SEQUENCE 312 AA; 34611 MW; 509919 CN; MKKSSIVATI ITILSGSANA ASSQLIPNIS PDSFTVAAST GMLSGKSHEM LYDAETGRKI SQLDWKIKNV AILKGDISWD PYSFLTLNAR GWTSLASGSG NMDDYDWMNE NQSEWTDHSS HPATNVNHAN EYDLNVKGWL LQDENYKAGI TAGYQETRFS WTATGGSYSY NNGAYTGNFP KGVRVIGYNQ RFSMPYIGLA GQYRINDFEL NALFKFSDWV RAHDNDEHYM RDLTFREKTS GSRYYGTVIN AGYYVTPNAK VFAEFTYSKY DEGKGGTQTI DKNSGDSVSI GGDAAGISNK NYTVTAGLQY RF //