ID SER3_DROME STANDARD; PRT; 61 AA. AC P17207; DT 01-AUG-1990 (Rel. 15, Created) DT 01-AUG-1990 (Rel. 15, Last sequence update) DT 01-NOV-1995 (Rel. 32, Last annotation update) DE SERINE PROTEASE 3 (EC 3.4.21.-) (FRAGMENT). GN SER3. OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Tracheata; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 89219063. RA YUN Y., DAVIS R.L.; RT "Levels of RNA from a family of putative serine protease genes are RT reduced in Drosophila melanogaster dunce mutants and are regulated by RT cyclic AMP."; RL Mol. Cell. Biol. 9:692-700(1989). CC -!- FUNCTION: ITS MAJOR FUNCTION MAY BE TO AID IN DIGESTION. CC -!- TISSUE SPECIFICITY: ABUNDANTLY EXPRESSED IN THE LARVAL GUT. CC -!- DEVELOPMENTAL STAGE: BEGAN TO APPEAR AT LATE EMBRYO STAGE AND CC CONTINUED TO INCREASE IN ABUNDANCE THROUGHOUT THE LARVAL STAGE. CC THEY ARE NOT PRESENT IN PUPAE BUT REAPPEARED IN THE ADULT. CC -!- SIMILARITY: BELONGS TO PEPTIDASE FAMILY S1; ALSO KNOWN AS THE CC TRYPSIN FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M24380; AAB02551.1; -. DR PIR; PS0049; PS0049. DR HSSP; P00760; 1AQ7. DR FLYBASE; FBgn0003358; Ser99Dc. DR PROSITE; PS00134; TRYPSIN_HIS; PARTIAL. DR PROSITE; PS00135; TRYPSIN_SER; 1. KW Hydrolase; Serine protease; Multigene family. FT NON_TER 1 1 FT ACT_SITE 11 11 CHARGE RELAY SYSTEM (BY SIMILARITY). SQ SEQUENCE 61 AA; 6495 MW; F93C454B CRC32; MDGKATCQGD SGGPLVTKEG DKLIGITSFV SAYGCQVGGP AGFTRVTKYL EWIKEETGIY Y //