ID UTXA_PEPDI Reviewed; 166 AA. AC P16153; DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot. DT 01-OCT-1996, sequence version 2. DT 16-SEP-2015, entry version 61. DE RecName: Full=Protein UtxA; GN Name=utxA; Synonyms=tcdE; OS Peptoclostridium difficile (Clostridium difficile). OC Bacteria; Firmicutes; Clostridia; Clostridiales; OC Peptostreptococcaceae; Peptoclostridium. OX NCBI_TaxID=1496; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 4325 / VPI 10463; RX PubMed=1603068; DOI=10.1007/BF00587587; RA von Eichel-Streiber C., Laufenberg-Feldmann R., Sartingen S., RA Schulze J., Sauerborn M.; RT "Comparative sequence analysis of the Clostridium difficile toxins A RT and B."; RL Mol. Gen. Genet. 233:260-268(1992). RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 4325 / VPI 10463; RX PubMed=2105276; RA Dove C.H., Wang S.-Z., Price S.B., Phelps C.J., Lyerly D.M., RA Wilkins T.D., Johnson J.L.; RT "Molecular characterization of the Clostridium difficile toxin A RT gene."; RL Infect. Immun. 58:480-488(1990). RN [3] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 4325 / VPI 10463; RA von Eichel-Streiber C.; RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 25-166. RC STRAIN=ATCC 4325 / VPI 10463; RX PubMed=2109310; DOI=10.1093/nar/18.6.1629; RA Sauerborn M., von Eichel-Streiber C.; RT "Nucleotide sequence of Clostridium difficile toxin A."; RL Nucleic Acids Res. 18:1629-1630(1990). CC -!- FUNCTION: May be involved in the regulation and/or secretion of CC toxins A and B. CC -!- ALTERNATIVE PRODUCTS: CC Event=Alternative initiation; Named isoforms=2; CC Name=Long; CC IsoId=P16153-1; Sequence=Displayed; CC Name=Short; CC IsoId=P16153-2; Sequence=VSP_018824; CC -!- SEQUENCE CAUTION: CC Sequence=AAA83533.1; Type=Erroneous initiation; Evidence={ECO:0000305}; CC Sequence=CAA36093.1; Type=Erroneous initiation; Evidence={ECO:0000305}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X60984; CAA43300.1; -; Genomic_DNA. DR EMBL; X60984; CAA43301.1; -; Genomic_DNA. DR EMBL; M30308; AAA83532.1; -; Genomic_DNA. DR EMBL; M30308; AAA83533.1; ALT_INIT; Genomic_DNA. DR EMBL; X92982; CAA63563.1; -; Genomic_DNA. DR EMBL; X51797; CAA36093.1; ALT_INIT; Genomic_DNA. DR PIR; B37052; B37052. DR RefSeq; WP_018112585.1; NZ_LN614756.1. DR ProteinModelPortal; P16153; -. DR STRING; 272563.CD0661; -. DR TCDB; 1.E.19.3.1; the clostridium difficile tcde holin (tcde holin) family. DR InterPro; IPR006480; Phage_phi-29_Gp14_holin. DR Pfam; PF05105; Phage_holin_4_1; 1. DR TIGRFAMs; TIGR01593; holin_tox_secr; 1. PE 4: Predicted; KW Alternative initiation. FT CHAIN 1 166 Protein UtxA. FT /FTId=PRO_0000022643. FT VAR_SEQ 1 26 Missing (in isoform Short). FT {ECO:0000305}. FT /FTId=VSP_018824. SQ SEQUENCE 166 AA; 18800 MW; 1671FAE1884C7EE2 CRC64; MHSSSPFYIS NGNKIFFYIN LGGVMNMTIS FLSEHIFIKL VILTISFDTL LGCLSAIKSR KFNSSFGIDG GIRKVAMIAC IFFLSVVDIL TKFNFLFMLP QDCINFLRLK HLGISEFFSI LFILYESVSI LKNMCLCGLP VPKRLKEKIA ILLDAMTDEM NAKDEK //