ID UTXA_CLODI STANDARD; PRT; 166 AA. AC P16153; DT 01-APR-1990 (Rel. 14, Created) DT 01-OCT-1996 (Rel. 34, Last sequence update) DT 10-MAY-2005 (Rel. 47, Last annotation update) DE Protein utxA. GN Name=utxA; Synonyms=tcdE; OS Clostridium difficile. OC Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; OC Clostridium. OX NCBI_TaxID=1496; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=VPI 10463; RX MEDLINE=92293124; PubMed=1603068; RA von Eichel-Streiber C., Laufenberg-Feldmann R., Sartingen S., RA Schulze J., Sauerborn M.; RT "Comparative sequence analysis of the Clostridium difficile toxins A RT and B."; RL Mol. Gen. Genet. 233:260-268(1992). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=VPI 10463; RX MEDLINE=90129305; PubMed=2105276; RA Dove C.H., Wang S.-Z., Price S.B., Phelps C.J., Lyerly D.M., RA Wilkins T.D., Johnson J.L.; RT "Molecular characterization of the Clostridium difficile toxin A RT gene."; RL Infect. Immun. 58:480-488(1990). RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=VPI 10463; RA von Eichel-Streiber C.; RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE OF 25-166. RC STRAIN=VPI 10463; RX MEDLINE=90221894; PubMed=2109310; RA Sauerborn M., von Eichel-Streiber C.; RT "Nucleotide sequence of Clostridium difficile toxin A."; RL Nucleic Acids Res. 18:1629-1630(1990). CC -!- FUNCTION: May be involved in the regulation and/or secretion of CC toxins A and B. CC -!- ALTERNATIVE PRODUCTS: CC Event=Alternative initiation; CC Comment=2 isoforms, Long (shown here) and Short, are produced by CC alternative initiation; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X60984; CAA43300.1; -; Genomic_DNA. DR EMBL; X60984; CAA43301.1; -; Genomic_DNA. DR EMBL; M30308; AAA83532.1; -; Genomic_DNA. DR EMBL; M30308; AAA83533.1; ALT_INIT; Genomic_DNA. DR EMBL; X92982; CAA63563.1; -; Genomic_DNA. DR EMBL; X51797; CAA36093.1; ALT_INIT; Genomic_DNA. DR PIR; B37052; B37052. DR InterPro; IPR006480; Holin_scret_tox. DR Pfam; PF05105; Phage_holin_4; 1. DR TIGRFAMs; TIGR01593; holin_tox_secr; 1. KW Alternative initiation. FT CHAIN 1 166 Protein utxA, isoform Long. FT /FTId=PRO_0000022643. FT CHAIN 27 166 Protein utxA, isoform Short. FT /FTId=PRO_0000022644. FT INIT_MET 27 27 For isoform Short. SQ SEQUENCE 166 AA; 18800 MW; 1671FAE1884C7EE2 CRC64; MHSSSPFYIS NGNKIFFYIN LGGVMNMTIS FLSEHIFIKL VILTISFDTL LGCLSAIKSR KFNSSFGIDG GIRKVAMIAC IFFLSVVDIL TKFNFLFMLP QDCINFLRLK HLGISEFFSI LFILYESVSI LKNMCLCGLP VPKRLKEKIA ILLDAMTDEM NAKDEK //