ID RPOA1_HALMO STANDARD; PRT; 349 AA. AC P15349; DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot. DT 01-APR-1990, sequence version 1. DT 07-MAR-2006, entry version 37. DE DNA-directed RNA polymerase subunit A' (EC 2.7.7.6) (Fragment). GN Name=rpoA1; OS Halococcus morrhuae. OC Archaea; Euryarchaeota; Halobacteria; Halobacteriales; OC Halobacteriaceae; Halococcus. OX NCBI_TaxID=2250; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 17082; RX MEDLINE=89199633; PubMed=2495365; RA Leffers H., Gropp F., Lottspeich F., Zillig W., Garrett R.A.; RT "Sequence, organization, transcription and evolution of RNA polymerase RT subunit genes from the archaebacterial extreme halophiles RT Halobacterium halobium and Halococcus morrhuae."; RL J. Mol. Biol. 206:1-17(1989). CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription CC of DNA into RNA using the four ribonucleoside triphosphates as CC substrates. CC -!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate CC + RNA(n+1). CC -!- COFACTOR: Zinc. CC -!- SUBUNIT: This RNA polymerase is composed of 5 large subunits: CC A',A'',B',B'' and epsilon, present in stoichiometric amounts, and CC 3 small ones, E, F and G, present in sub-stoichiometric amounts. CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X57145; CAA40431.1; -; Genomic_DNA. DR PIR; S03575; S03575. DR HSSP; P04050; 1I50. DR InterPro; IPR007066; RNA_pol_Rpb1_3. DR InterPro; IPR007083; RNA_pol_Rpb1_4. DR InterPro; IPR007081; RNA_pol_Rpb1_5. DR Pfam; PF04983; RNA_pol_Rpb1_3; 1. DR Pfam; PF05000; RNA_pol_Rpb1_4; 1. DR Pfam; PF04998; RNA_pol_Rpb1_5; 1. KW DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription; KW Transferase; Zinc. FT CHAIN <1 349 DNA-directed RNA polymerase subunit A'. FT /FTId=PRO_0000074002. FT CONFLICT 336 339 Missing (in Ref. 1; CAA40431). FT NON_TER 1 1 SQ SEQUENCE 349 AA; 38074 MW; 62EEA0E03C5D2ED1 CRC64; EFTSSTGDTV MIDEGALVEG TIDEDAVGAF GGEIVDTIVK QYGETRARVF INEVASLAMR AIMHFGFSIG IDDESISDAA EAQIDESMDN AYERVQELID TYENDDLESL PGRTVDETLE MKIMQTLGKA RDSAGDIADE HFDDDNPAVI MAESGARGSM LNLTQMAACV GQQAVRGERI NRGYEGRTLS HFKPGDLSAE AHGFVEDSYR SGLTPREFFF HAMGGREGLV DTAVRTSKSG YLQRRLINAL SELETQYDGT VRDTSDNIVQ FEFGEDNTSP VKVSSSDDNE IDVDEIADRV LAAEFEDEGE EFAGEQATNL SESADDRMDR DRPSSHGAAP IDVPEVGDD //