ID RPA1_HALMO STANDARD; PRT; 349 AA. AC P15349; DT 01-APR-1990 (Rel. 14, Created) DT 01-APR-1990 (Rel. 14, Last sequence update) DT 01-FEB-1996 (Rel. 33, Last annotation update) DE DNA-DIRECTED RNA POLYMERASE SUBUNIT A' (EC 2.7.7.6) (FRAGMENT). GN RPOA1. OS Halococcus morrhuae. OC Archaea; Euryarchaeota; Halobacteriales; Halobacteriaceae; Halococcus. OX NCBI_TaxID=2250; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=ATCC 17082; RX MEDLINE=89199633; PubMed=2495365; RA Leffers H., Gropp F., Lottspeich F., Zillig W., Garrett R.A.; RT "Sequence, organization, transcription and evolution of RNA RT polymerase subunit genes from the archaebacterial extreme halophiles RT Halobacterium halobium and Halococcus morrhuae."; RL J. Mol. Biol. 206:1-17(1989). CC -!- FUNCTION: DNA-DEPENDENT RNA POLYMERASE CATALYZES THE TRANSCRIPTION CC OF DNA INTO RNA USING THE FOUR RIBONUCLEOSIDE TRIPHOSPHATES AS CC SUBSTRATES. CC -!- CATALYTIC ACTIVITY: N NUCLEOSIDE TRIPHOSPHATE = N PYROPHOSPHATE + CC RNA(N). CC -!- COFACTOR: ZINC. CC -!- SUBUNIT: THIS RNA POLYMERASE IS COMPOSED OF 5 LARGE SUBUNITS: CC A',A",B',B" AND EPSILON, PRESENT IN STOICHIOMETRIC AMOUNTS, AND CC 3 SMALL ONES, E, F AND G, PRESENT IN SUB-STOICHIOMETRIC AMOUNTS. CC -!- SIMILARITY: THE COMBINED A'+A" SUBUNITS CORRESPOND TO THE A CC SUBUNITS OF EUKARYOTIC RNA POLYMERASES I, II AND III AND TO THE CC EUBACTERIAL BETA' SUBUNIT. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X57145; CAA40431.1; -. DR PIR; S03575; S03575. DR InterPro; IPR000722; -. DR Pfam; PF00623; RNA_pol_A; 1. KW Transferase; DNA-directed RNA polymerase; Transcription; Zinc. FT NON_TER 1 1 FT CONFLICT 336 339 MISSING (IN CAA40431). SQ SEQUENCE 349 AA; 38074 MW; 62EEA0E03C5D2ED1 CRC64; EFTSSTGDTV MIDEGALVEG TIDEDAVGAF GGEIVDTIVK QYGETRARVF INEVASLAMR AIMHFGFSIG IDDESISDAA EAQIDESMDN AYERVQELID TYENDDLESL PGRTVDETLE MKIMQTLGKA RDSAGDIADE HFDDDNPAVI MAESGARGSM LNLTQMAACV GQQAVRGERI NRGYEGRTLS HFKPGDLSAE AHGFVEDSYR SGLTPREFFF HAMGGREGLV DTAVRTSKSG YLQRRLINAL SELETQYDGT VRDTSDNIVQ FEFGEDNTSP VKVSSSDDNE IDVDEIADRV LAAEFEDEGE EFAGEQATNL SESADDRMDR DRPSSHGAAP IDVPEVGDD //