ID SCX2_BUTSI STANDARD; PRT; 28 AA. AC P15230; DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot. DT 01-APR-1990, sequence version 1. DT 17-OCT-2006, entry version 34. DE Peptide 2 (Peptide II). OS Buthus sindicus (Scorpion). OC Eukaryota; Metazoa; Arthropoda; Chelicerata; Arachnida; Scorpiones; OC Buthida; Buthoidea; Buthidae; Mesobuthus. OX NCBI_TaxID=42519; RN [1] RP PROTEIN SEQUENCE. RC TISSUE=Venom; RX MEDLINE=90060332; PubMed=2583272; DOI=10.1016/0014-5793(89)81548-0; RA Fazal A., Beg O.U., Shafqat J., Zaidi Z.H., Joernvall H.; RT "Characterization of two different peptides from the venom of the RT scorpion Buthus sindicus."; RL FEBS Lett. 257:260-262(1989). CC -!- FUNCTION: Blocks potassium channels (By similarity). CC -!- SUBCELLULAR LOCATION: Secreted protein. CC -!- TISSUE SPECIFICITY: Expressed by the venom gland. CC -!- SIMILARITY: Belongs to the short scorpion toxin superfamily. CC Potassium channel inhibitor family. Alpha-KTx 9 subfamily. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; S06668; S06668. DR HSSP; Q9NJP7; 1DU9. DR InterPro; IPR001947; Scorpion_toxinS. DR InterPro; IPR008911; Toxin_6. DR Pfam; PF05453; Toxin_6; 1. DR PROSITE; PS01138; SCORP_SHORT_TOXIN; FALSE_NEG. KW Direct protein sequencing; Ionic channel inhibitor; Neurotoxin; KW Potassium channel inhibitor; Toxin. FT PEPTIDE 1 28 Peptide 2. FT /FTId=PRO_0000044540. SQ SEQUENCE 28 AA; 2968 MW; 2EA9AD78BD39A3B8 CRC64; VGCEEDPMHC KGKQAKPTCC NGVCNCNV //