ID   HBA_PTEPO               Reviewed;         141 AA.
AC   P14390;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   03-OCT-2012, entry version 65.
DE   RecName: Full=Hemoglobin subunit alpha;
DE   AltName: Full=Alpha-globin;
DE   AltName: Full=Hemoglobin alpha chain;
GN   Name=HBA;
OS   Pteropus poliocephalus (Grey-headed flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Chiroptera; Megachiroptera;
OC   Pteropodidae; Pteropodinae; Pteropus.
OX   NCBI_TaxID=9403;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   MEDLINE=89149963; PubMed=3228493;
RA   Kleinschmidt T., Sgouros J.G., Pettigrew J.D., Braunitzer G.;
RT   "The primary structure of the hemoglobin from the grey-headed flying
RT   fox (Pteropus poliocephalus) and the black flying fox (P. alecto,
RT   Megachiroptera).";
RL   Biol. Chem. Hoppe-Seyler 369:975-984(1988).
CC   -!- FUNCTION: Involved in oxygen transport from the lung to the
CC       various peripheral tissues.
CC   -!- SUBUNIT: Heterotetramer of two alpha chains and two beta chains.
CC   -!- TISSUE SPECIFICITY: Red blood cells.
CC   -!- SIMILARITY: Belongs to the globin family.
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DR   PIR; S01310; HAFXG.
DR   ProteinModelPortal; P14390; -.
DR   SMR; P14390; 1-141.
DR   HOVERGEN; HBG009709; -.
DR   GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
DR   Gene3D; G3DSA:1.10.490.10; Globin_related; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like.
DR   InterPro; IPR012292; Globin_dom.
DR   InterPro; IPR002338; Haemoglobin_a.
DR   InterPro; IPR018331; Haemoglobin_alpha_chain.
DR   InterPro; IPR002339; Haemoglobin_pi.
DR   PANTHER; PTHR11442:SF14; PTHR11442:SF14; 1.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00612; ALPHAHAEM.
DR   PRINTS; PR00815; PIHAEM.
DR   SUPFAM; SSF46458; Globin_like; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Heme; Iron; Metal-binding;
KW   Oxygen transport; Transport.
FT   CHAIN         1    141       Hemoglobin subunit alpha.
FT                                /FTId=PRO_0000052745.
FT   METAL        58     58       Iron (heme distal ligand).
FT   METAL        87     87       Iron (heme proximal ligand).
SQ   SEQUENCE   141 AA;  15222 MW;  9F5AEF633458A46E CRC64;
     VLSSTDKSNV KAAWDKVGGN VGEYGAEALE RMFLSFPTTK TYFPHFDLAH GSSQVKAHGK
     KVGDALTNAV GHMDDLPGAL SALSDLHAYK LRVDPVNFKL LSHCLLVTLA NHLPNDFTPA
     VHASLDKFLA SVSTVLTSKY R
//