ID HBA_PTEPO STANDARD; PRT; 141 AA. AC P14390; DT 01-JAN-1990 (Rel. 13, Created) DT 01-JAN-1990 (Rel. 13, Last sequence update) DT 05-JUL-2004 (Rel. 44, Last annotation update) DE Hemoglobin alpha chain. GN Name=HBA; OS Pteropus poliocephalus (Grey-headed flying fox). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Chiroptera; Megachiroptera; Pteropodidae; OC Pteropodinae; Pteropus. OX NCBI_TaxID=9403; RN [1] RP SEQUENCE. RX MEDLINE=89149963; PubMed=3228493; RA Kleinschmidt T., Sgouros J.G., Pettigrew J.D., Braunitzer G.; RT "The primary structure of the hemoglobin from the grey-headed flying RT fox (Pteropus poliocephalus) and the black flying fox (P. alecto, RT Megachiroptera)."; RL Biol. Chem. Hoppe-Seyler 369:975-984(1988). CC -!- FUNCTION: Involved in oxygen transport from the lung to the CC various peripheral tissues. CC -!- SUBUNIT: Heterotetramer of two alpha chains and two beta chains. CC -!- TISSUE SPECIFICITY: Red blood cells. CC -!- SIMILARITY: Belongs to the globin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; S01310; HAFXG. DR HSSP; P01958; 1IWH. DR InterPro; IPR002338; Alpha_haem. DR InterPro; IPR000971; Globin. DR InterPro; IPR009050; Globin_like. DR InterPro; IPR002339; Pi_haem. DR Pfam; PF00042; Globin; 1. DR PRINTS; PR00612; ALPHAHAEM. DR PROSITE; PS01033; GLOBIN; 1. KW Heme; Oxygen transport; Transport; Erythrocyte; KW Direct protein sequencing. FT METAL 58 58 Iron (heme distal ligand). FT METAL 87 87 Iron (heme proximal ligand). SQ SEQUENCE 141 AA; 15222 MW; 9F5AEF633458A46E CRC64; VLSSTDKSNV KAAWDKVGGN VGEYGAEALE RMFLSFPTTK TYFPHFDLAH GSSQVKAHGK KVGDALTNAV GHMDDLPGAL SALSDLHAYK LRVDPVNFKL LSHCLLVTLA NHLPNDFTPA VHASLDKFLA SVSTVLTSKY R //