ID RL30_HALMA STANDARD; PRT; 154 AA. AC P14121; DT 01-JAN-1990 (Rel. 13, Created) DT 01-AUG-1992 (Rel. 23, Last sequence update) DT 25-OCT-2004 (Rel. 45, Last annotation update) DE 50S ribosomal protein L30P (Hmal30) (Hl20) (Hl16). GN Name=rpl30p; OS Haloarcula marismortui (Halobacterium marismortui). OC Archaea; Euryarchaeota; Halobacteria; Halobacteriales; OC Halobacteriaceae; Haloarcula. OX NCBI_TaxID=2238; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=91360093; PubMed=1832208; RA Scholzen T., Arndt E.; RT "Organization and nucleotide sequence of ten ribosomal protein genes RT from the region equivalent to the spectinomycin operon in the RT archaebacterium Halobacterium marismortui."; RL Mol. Gen. Genet. 228:70-80(1991). RN [2] RP PROTEIN SEQUENCE. RX MEDLINE=90076190; PubMed=2591382; RA Hatakeyama T., Kaufmann F., Schroeter B., Hatakeyama T.; RT "Primary structures of five ribosomal proteins from the RT archaebacterium Halobacterium marismortui and their structural RT relationships to eubacterial and eukaryotic ribosomal proteins."; RL Eur. J. Biochem. 185:685-693(1989). RN [3] RP PROTEIN SEQUENCE OF 1-30. RX MEDLINE=89062418; PubMed=3196689; RA Walsh M.J., McDougall J., Wittmann-Liebold B.; RT "Extended N-terminal sequencing of proteins of archaebacterial RT ribosomes blotted from two-dimensional gels onto glass fiber and RT poly(vinylidene difluoride) membrane."; RL Biochemistry 27:6867-6876(1988). RN [4] RP X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF THE 50S SUBUNIT. RC STRAIN=ATCC 43049; RX MEDLINE=20396344; PubMed=10937989; DOI=10.1126/science.289.5481.905; RA Ban N., Nissen P., Hansen J., Moore P.B., Steitz T.A.; RT "The complete atomic structure of the large ribosomal subunit at 2.4 A RT resolution."; RL Science 289:905-920(2000). RN [5] RP X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT. RC STRAIN=ATCC 43049; RX PubMed=10937990; DOI=10.1126/science.289.5481.920; RA Nissen P., Hansen J., Ban N., Moore P.B., Steitz T.A.; RT "The structural basis of ribosome activity in peptide bond RT synthesis."; RL Science 289:920-930(2000). RN [6] RP X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF THE 50S SUBUNIT. RC STRAIN=ATCC 43049; RX PubMed=11828326; DOI=10.1038/nsb758; RA Schmeing T.M., Seila A.C., Hansen J.L., Freeborn B., Soukup J.K., RA Scaringe S.A., Strobel S.A., Moore P.B., Steitz T.A.; RT "A pre-translocational intermediate in protein synthesis observed in RT crystals of enzymatically active 50S subunits."; RL Nat. Struct. Biol. 9:225-230(2002). RN [7] RP X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF THE 50S SUBUNIT. RC STRAIN=ATCC 43049; RX PubMed=11483524; DOI=10.1093/emboj/20.15.4214; RA Klein D.J., Schmeing T.M., Moore P.B., Steitz T.A.; RT "The kink-turn: a new RNA secondary structure motif."; RL EMBO J. 20:4214-4221(2001). RN [8] RP X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX RP WITH FOUR MACROLIDE ANTIBIOTICS. RC STRAIN=ATCC 43049; RX PubMed=12150912; DOI=10.1016/S1097-2765(02)00570-1; RA Hansen J.L., Ippolito J.A., Ban N., Nissen P., Moore P.B., RA Steitz T.A.; RT "The structures of four macrolide antibiotics bound to the large RT ribosomal subunit."; RL Mol. Cell 10:117-128(2002). RN [9] RP X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF THE 50S SUBUNIT. RC STRAIN=ATCC 43049; RX PubMed=12185246; DOI=10.1073/pnas.172404099; RA Hansen J.L., Schmeing T.M., Moore P.B., Steitz T.A.; RT "Structural insights into peptide bond formation."; RL Proc. Natl. Acad. Sci. U.S.A. 99:11670-11675(2002). RN [10] RP X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX RP WITH FIVE ANTIBIOTICS AT THE PEPTIDYL TRANSFERASE CENTER. RC STRAIN=ATCC 43049; RX PubMed=12860128; DOI=10.1016/S0022-2836(03)00668-5; RA Hansen J.L., Moore P.B., Steitz T.A.; RT "Structures of five antibiotics bound at the peptidyl transferase RT center of the large ribosomal subunit."; RL J. Mol. Biol. 330:1061-1075(2003). RN [11] RP X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF THE 50S SUBUNIT WITH TWO RP DIFFERENT E SITE SUBSTRATES. RX PubMed=14561884; DOI=10.1261/rna.5120503; RA Schmeing T.M., Moore P.B., Steitz T.A.; RT "Structures of deacylated tRNA mimics bound to the E site of the large RT ribosomal subunit."; RL RNA 9:1345-1352(2003). CC -!- FUNCTION: This is one of 5 proteins that mediate the attachment of CC the 5S rRNA onto the large ribosomal subunit, stabilizing the CC orientation of adjacent RNA domains. CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Binds 5S rRNA. CC -!- SIMILARITY: Belongs to the ribosomal protein L30P family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X58395; CAA41292.1; -. DR PIR; S16543; R5HS30. DR PDB; 1FFK; X-ray; T=-. DR PDB; 1JJ2; X-ray; V=1-154. DR PDB; 1K73; X-ray; X=-. DR PDB; 1K8A; X-ray; X=1-154. DR PDB; 1K9M; X-ray; X=1-154. DR PDB; 1KC8; X-ray; X=1-154. DR PDB; 1KD1; X-ray; X=1-154. DR PDB; 1KQS; X-ray; V=-. DR PDB; 1M1K; X-ray; X=1-154. DR PDB; 1M90; X-ray; X=1-154. DR PDB; 1N8R; X-ray; X=1-154. DR PDB; 1NJI; X-ray; X=1-154. DR PDB; 1Q7Y; X-ray; X=1-154. DR PDB; 1Q81; X-ray; X=1-154. DR PDB; 1Q82; X-ray; X=1-154. DR PDB; 1Q86; X-ray; X=1-154. DR PDB; 1QVF; X-ray; V=1-154. DR PDB; 1QVG; X-ray; V=1-154. DR InterPro; IPR000517; Ribosomal_L30. DR InterPro; IPR005997; Ribosomal_L30_a. DR Pfam; PF00327; Ribosomal_L30; 1. DR TIGRFAMs; TIGR01309; L30P_arch; 1. DR PROSITE; PS00634; RIBOSOMAL_L30; 1. KW 3D-structure; Direct protein sequencing; Ribosomal protein; KW RNA-binding; rRNA-binding. FT CONFLICT 83 83 W -> L (in Ref. 2). FT CONFLICT 148 148 Missing (in Ref. 2). SQ SEQUENCE 154 AA; 17042 MW; ED673F036E974C14 CRC64; MHALVQLRGE VNMHTDIQDT LEMLNIHHVN HCTLVPETDA YRGMVAKVND FVAFGEPSQE TLETVLATRA EPLEGDADVD DEWVAEHTDY DDISGLAFAL LSEETTLREQ GLSPTLRLHP PRGGHDGVKH PVKEGGQLGK HDTEGIDDLL EAMR //