ID PLST$HUMAN STANDARD; PRT; 570 AA. AC P13797; DT 01-JAN-1990 (REL. 13, CREATED) DT 01-JAN-1990 (REL. 13, LAST SEQUENCE UPDATE) DT 01-NOV-1990 (REL. 16, LAST ANNOTATION UPDATE) DE T-PLASTIN POLYPEPTIDE PRECURSOR. OS HUMAN (HOMO SAPIENS). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA; OC EUTHERIA; PRIMATES. RN [1] (SEQUENCE FROM N.A., AND PARTIAL SEQUENCE) RA LIN C.-S., AEBERSOLD R.H., KENT S.B., VARMA M., LEAVITT J.; RL MOL. CELL. BIOL. 8:4659-4668(1988). CC -!- THERE EXIST AT LEAST TWO ISOFORMS OF PLASTIN, L-PLASTIN CC AND T-PLASTIN. THEIR EXPRESSION IS REGULATED IN A TISSUE- CC SPECIFIC MANNER. L-PLASTIN IS NORMALLY ABUNDANT IN CC LEUCOCYTES AND T-PLASTIN OCCURS ON NORMAL AND TRANSFORMED CC FIBROBLASTS, BUT NOT ON LEUCOCYTES. CC -!- SIMILARITY: 83% TO PLASTIN-L (P13796). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M22299; HSPLAST. DR PIR; B31559; B31559. DR PROSITE; PS00018; EF_HAND. KW CALCIUM-BINDING; PHOSPHORYLATION. FT PEPTIDE 85 131 T-PLASTIN PEPTIDE 1. FT PEPTIDE 132 180 T-PLASTIN PEPTIDE 2. FT PEPTIDE 181 355 T-PLASTIN PEPTIDE 3. FT PEPTIDE 356 415 T-PLASTIN PEPTIDE 4. FT PEPTIDE 416 458 T-PLASTIN PEPTIDE 5. FT PEPTIDE 459 487 T-PLASTIN PEPTIDE 6. FT PEPTIDE 488 539 T-PLASTIN PEPTIDE 7. FT PEPTIDE 540 570 T-PLASTIN PEPTIDE 8. SQ SEQUENCE 570 AA; 63865 MW; 1606447 CN; MLDGDRNKDG KISFDEFVYI FQEVKSSDIA KTFRKAINRK EGICALGGTS ELSSEGTQHS YSEEEKYAFV NWINKALEND PDCRHVIPMN PNTDDLFKAV GDGIVLCKMI NLSVPDTIDE RAINKKKLTP FIIQENLNLA LNSASAIGCH VVNIGAEDLR AGKPHLVLGL LWQIIKIGLF ADIELSRNEA LAALLRDGET LEELMKLSPE ELLLRWANFH LENSGWQKIN NFSADIKDSK AYFHLLNQIA PKGQKEGEPR IDINMSGFNE TDDLKRAESM LQQADKLGCR QFVTPADVVS GNPKLNLAFV ANLFNKYPAL TKPENQDIDW TLLEGETREE RTFRNWMNSL GVNPHVNHLY ADLQDALVIL QLYERIKVPV DWSKVNKPPY PKLGANMKKL ENCNYAVELG KHPAKFSLVG IGGQDLNDGN QTLTLALVWQ LMRRYTLNVL EDLGDGQKAN DDIIVNWVNR TLSEAGKSTS IQSFKDKTIS SSLAVVDLID AIQPGCINYD LVKSGNLTED DKHNNAKYAV SMARRIGARV YALPEDLVEV KPKMVMTVFA CLMGRGMKRV //