ID MYSP_DIRIM STANDARD; PRT; 848 AA. AC P13392; DT 01-JAN-1990 (REL. 13, CREATED) DT 01-JUN-1994 (REL. 29, LAST SEQUENCE UPDATE) DT 01-JUN-1994 (REL. 29, LAST ANNOTATION UPDATE) DE PARAMYOSIN (FRAGMENT). OS DIROFILARIA IMMITIS. OC EUKARYOTA; METAZOA; ACOELOMATES; NEMATODA; SECERNENTEA; SPIRURIDA. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 90220759. RA LIMBERGER R.J., MCREYNOLDS L.A.; RL MOL. BIOCHEM. PARASITOL. 38:271-280(1990). RN [2] RP SEQUENCE OF 18-96 FROM N.A. RX MEDLINE; 89344126. RA GRANDEA A.G. III, TUYEN L.K., ASIKIN N., DAVIS T.B., PHILIPP M., RA COHEN C., MCREYNOLDS L.A.; RL MOL. BIOCHEM. PARASITOL. 35:31-41(1989). CC -!- FUNCTION: PARAMYOSIN IS A MAJOR STRUCTURAL COMPONENT OF CC MANY THICK FILAMENTS ISOLATED FROM INVERTEBRATE MUSCLES. CC -!- SUBCELLULAR LOCATION: THICK FILAMENTS OF THE MYOFIBRILS. CC -!- SUBUNIT: HOMODIMER (BY SIMILARITY). CC -!- SIMILARITY: HIGH, TO MYOSIN HEAVY CHAINS. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M29733; G537506; -. DR EMBL; J04009; G156710; -. DR PIR; A45548; A45548. DR PIR; A44972; A44972. KW COILED COIL; HEPTAD REPEAT PATTERN; MUSCLE PROTEIN; THICK FILAMENT; KW MYOSIN. FT NON_TER 1 1 FT DOMAIN <1 8 NON-HELICAL REGION (POTENTIAL). FT DOMAIN 9 825 COILED COIL (POTENTIAL). FT DOMAIN 826 848 NON-HELICAL REGION (POTENTIAL). FT DISULFID 105 105 INTERCHAIN (POTENTIAL). FT DISULFID 594 594 INTERCHAIN (POTENTIAL). FT NON_TER 848 848 SQ SEQUENCE 848 AA; 98008 MW; 0801F019 CRC32; AFGSMSVADL GSLTRLEDKI RLLQEDLESE RELRNRIERE RADLSVQLIA LTDRLEDAEG TTDSQIESNR KREAELQKLR KLLEESQLEN EDAMNVLRKK HQDACLDYAE QIEQLQKKNS KIDRERQRLQ HEVIELTATI DQLQKDKHLA EKAAERFEAQ TIELSNKVED LNRHVNDLAQ QRQRLQAENN DLLKEIHDQK VQLDNLQHVK YQLAQQLEEA RRRLEDAERE RSQLQAQLHQ VQLELDSVRT ALDEESAARA EAEHKLALAN TEITQWKSKF DAEVALHHEE VEDLRKKMLQ KQAEYEEQIE IMLQKISQLE KAKSRLQSEV EVLIVDLEKA QNTIAILERA KEQLEKTVNE LKVRIDELTV ELEAAQREAR AALAELQKMK NLYEKAIEQK EALARENKKL QDDLHEAKEA LADANRKLHE LDLENARLAG EIRELQTALK ESEAARRDAE NRAQRALAEL QQLRIEMERR LQEKEEEMEA LRKNMQFEID RLTAALADAE ARMKAEISRL KKKYQAEIAE LEMTVDNLNR ANIEAQKTIK KQSEQLKILQ ASLEDTQRQL QQTLDQYALA QRKVSALSAE LEECKVALDN AIRARKQAEI DLEEANARIT DLVSINNNLT AIKNKLETEL STAQADLDEA TKELHAADER ANRALADAAR AVEQLHEEQE HSMKIDALRK SLEEQVKQLQ VQIQEAEAAA LLGGKRVIAK LETRIRDLET ALDEETRRHK ETQGALRKKD RRIKEVQMQV DEEHKMFVMA QDTADRLLEK LNIQKWQLGE AESLTMANLQ RVRRYQRELE DAEGRADQAE SSLHLIRAKH RSSVVTGKNA SASKIYVL //