ID LEC1_LATOC STANDARD; PRT; 53 AA. AC P12306; DT 01-OCT-1989 (Rel. 12, Created) DT 01-OCT-1989 (Rel. 12, Last sequence update) DT 01-MAY-2005 (Rel. 47, Last annotation update) DE Mannose/glucose-specific lectin alpha 1 chain (Lol I). OS Lathyrus ochrus (Yellow-flowered pea). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicots; rosids; OC eurosids I; Fabales; Fabaceae; Papilionoideae; Vicieae; Lathyrus. OX NCBI_TaxID=3858; RN [1] RP PROTEIN SEQUENCE. RX MEDLINE=85004103; PubMed=6383863; DOI=10.1016/0014-5793(84)80573-6; RA Richardson M., Rouge P., Sousa-Cavada B., Yarwood A.; RT "The amino acid sequences of the alpha 1 and alpha 2 subunits of the RT isolectins from seeds of Lathyrus ochrus (L) DC."; RL FEBS Lett. 175:76-81(1984). RN [2] RP X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS). RX MEDLINE=90339494; PubMed=2380988; RA Bourne Y., Abergel C., Cambillau C., Frey M., Rouge P., RA Fontecilla-Camps J.-C.; RT "X-ray crystal structure determination and refinement at 1.9-A RT resolution of isolectin I from the seeds of Lathyrus ochrus."; RL J. Mol. Biol. 214:571-584(1990). RN [3] RP X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS). RX MEDLINE=91219398; PubMed=2091026; RA Bourne Y., Roussel A., Frey M., Rouge P., Fontecilla-Camps J.-C., RA Cambillau C.; RT "Three-dimensional structures of complexes of Lathyrus ochrus RT isolectin I with glucose and mannose: fine specificity of the RT monosaccharide-binding site."; RL Proteins 8:365-376(1990). CC -!- SUBUNIT: Tetramer of two alpha and two beta chains. CC -!- SIMILARITY: Belongs to the leguminous lectin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; A25989; A25989. DR PDB; 1LOA; X-ray; B/D/F/H=1-52. DR PDB; 1LOB; X-ray; B/D/F/H=1-52. DR PDB; 1LOC; X-ray; B/D/F/H=1-52. DR PDB; 1LOD; X-ray; B/D/F/H=1-52. DR PDB; 1LOE; X-ray; B/D=1-52. DR PDB; 1LOF; X-ray; B=1-52, D=1-51. DR PDB; 1LOG; X-ray; B/D=1-52. DR InterPro; IPR008985; ConA_like_lec_gl. DR InterPro; IPR000985; Lectin_legA. DR Pfam; PF00138; Lectin_legA; 1. DR ProDom; PD000671; Lectin_legA; 1. DR PROSITE; PS00308; LECTIN_LEGUME_ALPHA; 1. KW 3D-structure; Direct protein sequencing; Lectin; Mannose-binding. FT STRAND 3 9 FT HELIX 12 15 FT STRAND 19 27 FT STRAND 34 46 SQ SEQUENCE 53 AA; 5877 MW; 06E19D2C33444961 CRC64; ETSYTLNEVV PLKEFVPEWV RIGFSATTGA EFAAHEVLSW FFHSELAGTS SSN //