ID MCRB$METTH STANDARD; PRT; 426 AA. AC P11560; DT 01-OCT-1989 (REL. 12, CREATED) DT 01-OCT-1989 (REL. 12, LAST SEQUENCE UPDATE) DT 01-OCT-1989 (REL. 12, LAST ANNOTATION UPDATE) DE METHYL COENZYME M REDUCTASE COMPONENT C BETA SUBUNIT (GENE NAME: DE MCRB). OS METHANOBACTERIUM THERMOAUTOTROPHICUM. OC PROKARYOTA; MENDOSICUTES; ARCHAEBACTERIA; METHANOBACTERIALES; OC METHANOBACTERIACEAE. RN [1] (STRAIN MARBURG, SEQUENCE FROM N.A.) RA BOKRANZ M., BAEUMNER G., ALLMANSBERGER R., ANKEL-FUCHS D., KLEIN A.; RL J. BACTERIOL. 170:568-577(1988). CC -!- FUNCTION: THIS ENZYME COMPLEX CATALYZES THE FINAL STEP IN CC METHANOGENESIS, WHICH IS THE TERMINAL STEP OF ANAEROBIC CC DEGRADATION OF BIOMASS. CC -!- CATALYTIC ACTIVITY: REDUCTION OF CH(3) MOIETY OF 2-(METHYLTHIO) CC ETHANESULFONIC ACID, RESULTING IN THE RELEASE OF METHANE. CC -!- THIS COMPLEX ENZYME HAS BEEN RESOLVED BY PURIFICATION INTO CC PROTEIN COMPONENTS A AND C AND A SMALL COFACTOR, COMPONENT B. CC COMPONENT C IS THOUGHT TO BE THE ACTUAL SITE OF METHYL GROUP CC REDUCTION. CC -!- SUBUNIT: COMPONENT C IS COMPOSED OF THREE SUBUNITS: ALPHA, BETA, CC AND GAMMA. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X07794; MTMCR. KW METHANOGENESIS; OXIDOREDUCTASE. SQ SEQUENCE 426 AA; 45341 MW; 902786 CN; MAKFEDKVDL YDDRGNLVEE QVPLEALSPL RNPAIKSIVQ GIKRTVAVNL EGIENALKTA KVGGPACKIM GRELDLDIVG NAESIAAAAK EMIQVTEDDD TNVELLGGGK RALVQVPSAR FDVAAEYSAA PLVTATAFVQ AIINEFDVSM YDANMVKAAV LGRYPQSVEY MGANIATMLD IPQKLEGPGY ALRNIMVNHV VAATLKNTLQ AAALSTILEQ TAMFEMGDAV GAFERMHLLG LAYQGMNADN LVFDLVKANG KEGTVGSVIA DLVERALEDG VIKVEKELTD YKVYGTDDLA MWNAYAAAGL MAATMVNQGA ARAAQGVSST LLYYNDLIEF ETGLPSVDFG KVEGTAVGFS FFSHSIYGGG GPGIFNGNHI VTRHSKGFAI PCVAAAMALD AGTQMFSPEA TSGLIKEVFS QVDEFR //