ID BPHC$PSEPA STANDARD; PRT; 299 AA. AC P11122; DT 01-JUL-1989 (REL. 11, CREATED) DT 01-JUL-1989 (REL. 11, LAST SEQUENCE UPDATE) DT 01-JAN-1990 (REL. 13, LAST ANNOTATION UPDATE) DE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE (EC 1.13.11.39) (23OHBP OXYGENASE) DE (2,3-DIHYDROXYBIPHENYL DIOXYGENASE) (GENE NAME: BPHC). OS PSEUDOMONAS PAUCIMOBILIS. OC PROKARYOTA; GRACILICUTES; SCOTOBACTERIA; AEROBIC RODS AND COCCI; OC PSEUDOMONADACEAE. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=Q1; RC MEDLINE=88326911; RA TAIRA K., HAYASE N., ARIMURA N., YAMASHITA S., MIYAZAKI T., RA FURUKAWA K.; RL BIOCHEMISTRY 27:3990-3996(1988). CC -!- CATALYTIC ACTIVITY: BIPHENYL-2,3-DIOL + O(2) = 2-HYDROXY-6-OXO- CC 6-PHENYLHEXA-2,4-DIENOATE + H(2)O. CC -!- PATHWAY: DEGRADATION OF BIPHENYLS AND POLYCHLOROBIPHENYLS (PCB) TO CC BENZOIC ACID AND CHLOROBENZOIC ACIDS. CC -!- SUBUNIT: HOMOOCTAMER. CC -!- SIMILARITY: TO PSEUDOMONAS PSEUDOALCALIGENES BIPHENYL-2,3-DIOL CC 1,2-DIOXYGENASE AND CATECHOL 2,3-DIOXYGENASE. CC -!- COFACTOR: REQUIRES FERROUS IRON AS THE PROSTHETIC GROUP. CC -!- SIMILARITY: HIGH WITH 3-METHYLCATECHOL 2,3-DIOXYGENASE. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M20640; PP23OHBP. DR PIR; A28718; A28718. DR PROSITE; PS00082; EXTRADIOL_DIOXYGENAS. KW OXIDOREDUCTASE; DIOXYGENASE; AROMATIC HYDROCARBONS CATABOLISM; IRON. SQ SEQUENCE 299 AA; 33095 MW; 424483 CN; MVAVTELGYL GLTVTNLDAW RSYAAEVAGM EIVDEGEGDR LYLRMDQWHH RIVLHASDSD DLAYLGWRVA DPVEFDAMVA KLTAAGISLT VASEAEARER RVLGLAKLAD PGGNPTEIFY GPQVDTHKPF HPGRPMYGKF VTGSEGIGHC ILRQDDVPAA AAFYGLLGLR GSVEYHLQLP NGMVAQPYFM HCNERQHSVA FGLGPMEKRI NHLMFEYTDL DDLGLAHDIV RARKIDVALQ LGKHANDQAL TFYCANPSGW LWEFGWGARK APSQQEYYTR DIFGHGNEAA GYGMDIPLG //