ID BPHC_PSEPA STANDARD; PRT; 299 AA. AC P11122; DT 01-JUL-1989 (Rel. 11, Created) DT 01-JUL-1989 (Rel. 11, Last sequence update) DT 15-JUL-1999 (Rel. 38, Last annotation update) DE Biphenyl-2,3-diol 1,2-dioxygenase (EC 1.13.11.39) (23OHBP oxygenase) DE (2,3-dihydroxybiphenyl dioxygenase) (DHBD). GN BPHC. OS Pseudomonas paucimobilis (Sphingomonas paucimobilis). OC Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales; OC Sphingomonadaceae; Sphingomonas. OX NCBI_TaxID=13689; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=Q1; RX MEDLINE=88326911; PubMed=3137968; RA Taira K., Hayase N., Arimura N., Yamashita S., Miyazaki T., RA Furukawa K.; RT "Cloning and nucleotide sequence of the 2,3-dihydroxybiphenyl RT dioxygenase gene from the PCB-degrading strain of Pseudomonas RT paucimobilis Q1."; RL Biochemistry 27:3990-3996(1988). CC -!- CATALYTIC ACTIVITY: Biphenyl-2,3-diol + O(2) = 2-hydroxy-6-oxo-6- CC phenylhexa-2,4-dienoate + H(2)O. CC -!- COFACTOR: Ferrous ion. CC -!- PATHWAY: Degradation of biphenyls and polychlorobiphenyls (PCB) to CC benzoic acid and chlorobenzoic acids. CC -!- SUBUNIT: Homooctamer. CC -!- SIMILARITY: Belongs to the extradiol ring-cleavage dioxygenase CC family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M20640; AAA25678.1; -. DR PIR; A28718; A28718. DR HSSP; P17297; 1DHY. DR InterPro; IPR004360; Gly_bleo_diox. DR InterPro; IPR000486; Xdiol_dioxygnse. DR Pfam; PF00903; Glyoxalase; 2. DR ProDom; PD000977; Xdiol_dioxygnse; 1. DR PROSITE; PS00082; EXTRADIOL_DIOXYGENAS; 1. KW Oxidoreductase; Dioxygenase; Aromatic hydrocarbons catabolism; Iron. FT METAL 149 149 IRON (BY SIMILARITY). FT METAL 212 212 IRON (BY SIMILARITY). FT METAL 263 263 IRON (BY SIMILARITY). SQ SEQUENCE 299 AA; 33095 MW; 29746CAB79D6FC7B CRC64; MVAVTELGYL GLTVTNLDAW RSYAAEVAGM EIVDEGEGDR LYLRMDQWHH RIVLHASDSD DLAYLGWRVA DPVEFDAMVA KLTAAGISLT VASEAEARER RVLGLAKLAD PGGNPTEIFY GPQVDTHKPF HPGRPMYGKF VTGSEGIGHC ILRQDDVPAA AAFYGLLGLR GSVEYHLQLP NGMVAQPYFM HCNERQHSVA FGLGPMEKRI NHLMFEYTDL DDLGLAHDIV RARKIDVALQ LGKHANDQAL TFYCANPSGW LWEFGWGARK APSQQEYYTR DIFGHGNEAA GYGMDIPLG //