ID BPHC_PSEPA STANDARD; PRT; 299 AA. AC P11122; DT 01-JUL-1989 (Rel. 11, Created) DT 01-JUL-1989 (Rel. 11, Last sequence update) DT 15-JUL-1999 (Rel. 38, Last annotation update) DE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE (EC 1.13.11.39) (23OHBP OXYGENASE) DE (2,3-DIHYDROXYBIPHENYL DIOXYGENASE) (DHBD). GN BPHC. OS Pseudomonas paucimobilis (Sphingomonas paucimobilis). OC Bacteria; Proteobacteria; alpha subdivision; Sphingomonas group; OC Sphingomonas. OX NCBI_TaxID=13689; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=Q1; RX MEDLINE=88326911; PubMed=3137968; RA Taira K., Hayase N., Arimura N., Yamashita S., Miyazaki T., RA Furukawa K.; RT "Cloning and nucleotide sequence of the 2,3-dihydroxybiphenyl RT dioxygenase gene from the PCB-degrading strain of Pseudomonas RT paucimobilis Q1."; RL Biochemistry 27:3990-3996(1988). CC -!- CATALYTIC ACTIVITY: BIPHENYL-2,3-DIOL + O(2) = 2-HYDROXY-6-OXO- CC 6-PHENYLHEXA-2,4-DIENOATE + H(2)O. CC -!- COFACTOR: FERROUS ION. CC -!- PATHWAY: DEGRADATION OF BIPHENYLS AND POLYCHLOROBIPHENYLS (PCB) TO CC BENZOIC ACID AND CHLOROBENZOIC ACIDS. CC -!- SUBUNIT: HOMOOCTAMER. CC -!- SIMILARITY: BELONGS TO THE EXTRADIOL RING-CLEAVAGE DIOXYGENASE CC FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M20640; AAA25678.1; -. DR PIR; A28718; A28718. DR HSSP; P17297; 1DHY. DR InterPro; IPR000486; Extradiol_dioxygnse. DR InterPro; IPR000325; Glyoxalase_1. DR Pfam; PF00903; Glyoxalase; 2. DR ProDom; PD000977; -; 1. DR PROSITE; PS00082; EXTRADIOL_DIOXYGENAS; 1. KW Oxidoreductase; Dioxygenase; Aromatic hydrocarbons catabolism; Iron. FT METAL 149 149 IRON (BY SIMILARITY). FT METAL 212 212 IRON (BY SIMILARITY). FT METAL 263 263 IRON (BY SIMILARITY). SQ SEQUENCE 299 AA; 33095 MW; 29746CAB79D6FC7B CRC64; MVAVTELGYL GLTVTNLDAW RSYAAEVAGM EIVDEGEGDR LYLRMDQWHH RIVLHASDSD DLAYLGWRVA DPVEFDAMVA KLTAAGISLT VASEAEARER RVLGLAKLAD PGGNPTEIFY GPQVDTHKPF HPGRPMYGKF VTGSEGIGHC ILRQDDVPAA AAFYGLLGLR GSVEYHLQLP NGMVAQPYFM HCNERQHSVA FGLGPMEKRI NHLMFEYTDL DDLGLAHDIV RARKIDVALQ LGKHANDQAL TFYCANPSGW LWEFGWGARK APSQQEYYTR DIFGHGNEAA GYGMDIPLG //