ID BPHC_PSEPA STANDARD; PRT; 299 AA. AC P11122; DT 01-JUL-1989 (REL. 11, CREATED) DT 01-JUL-1989 (REL. 11, LAST SEQUENCE UPDATE) DT 01-NOV-1995 (REL. 32, LAST ANNOTATION UPDATE) DE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE (EC 1.13.11.39) (23OHBP OXYGENASE) DE (2,3-DIHYDROXYBIPHENYL DIOXYGENASE) (DHBD). GN BPHC. OS PSEUDOMONAS PAUCIMOBILIS (SPHINGOMONAS PAUCIMOBILIS). OC BACTERIA; PROTEOBACTERIA; ALPHA SUBDIVISION; ZYMOMONAS GROUP; OC SPHINGOMONAS. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=Q1; RX MEDLINE; 88326911. RA TAIRA K., HAYASE N., ARIMURA N., YAMASHITA S., MIYAZAKI T., RA FURUKAWA K.; RT "Cloning and nucleotide sequence of the 2,3-dihydroxybiphenyl RT dioxygenase gene from the PCB-degrading strain of Pseudomonas RT paucimobilis Q1."; RL BIOCHEMISTRY 27:3990-3996(1988). CC -!- CATALYTIC ACTIVITY: BIPHENYL-2,3-DIOL + O(2) = 2-HYDROXY-6-OXO- CC 6-PHENYLHEXA-2,4-DIENOATE + H(2)O. CC -!- COFACTOR: REQUIRES FERROUS IRON AS THE PROSTHETIC GROUP. CC -!- PATHWAY: DEGRADATION OF BIPHENYLS AND POLYCHLOROBIPHENYLS (PCB) TO CC BENZOIC ACID AND CHLOROBENZOIC ACIDS. CC -!- SUBUNIT: HOMOOCTAMER. CC -!- SIMILARITY: BELONGS TO THE EXTRADIOL RING-CLEAVAGE DIOXYGENASE CC FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M20640; G150948; -. DR PIR; A28718; A28718. DR PROSITE; PS00082; EXTRADIOL_DIOXYGENAS; 1. DR PFAM; PF01013; Extradiol_dioxy; 1. DR HSSP; P17297; 1DHY. KW OXIDOREDUCTASE; DIOXYGENASE; AROMATIC HYDROCARBONS CATABOLISM; IRON. FT METAL 149 149 IRON (BY SIMILARITY). FT METAL 212 212 IRON (BY SIMILARITY). FT METAL 263 263 IRON (BY SIMILARITY). SQ SEQUENCE 299 AA; 33095 MW; E5EAAE3B CRC32; MVAVTELGYL GLTVTNLDAW RSYAAEVAGM EIVDEGEGDR LYLRMDQWHH RIVLHASDSD DLAYLGWRVA DPVEFDAMVA KLTAAGISLT VASEAEARER RVLGLAKLAD PGGNPTEIFY GPQVDTHKPF HPGRPMYGKF VTGSEGIGHC ILRQDDVPAA AAFYGLLGLR GSVEYHLQLP NGMVAQPYFM HCNERQHSVA FGLGPMEKRI NHLMFEYTDL DDLGLAHDIV RARKIDVALQ LGKHANDQAL TFYCANPSGW LWEFGWGARK APSQQEYYTR DIFGHGNEAA GYGMDIPLG //