ID RL23_ECOLI Reviewed; 100 AA. AC P0ADZ0; P02424; Q2M6Y3; DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot. DT 06-DEC-2005, sequence version 1. DT 31-OCT-2006, entry version 14. DE 50S ribosomal protein L23. GN Name=rplW; OrderedLocusNames=b3318, JW3280; OS Escherichia coli. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Escherichia. OX NCBI_TaxID=562; RN [1] RP PROTEIN SEQUENCE. RC STRAIN=K12; RX MEDLINE=80092111; PubMed=391594; DOI=10.1016/0014-5793(79)81181-3; RA Wittmann-Liebold B., Greuer B.; RT "Primary structure of protein L23 from the Escherichia coli RT ribosome."; RL FEBS Lett. 108:69-74(1979). RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX MEDLINE=85242118; PubMed=3892488; RA Zurawski G., Zurawski S.M.; RT "Structure of the Escherichia coli S10 ribosomal protein operon."; RL Nucleic Acids Res. 13:4521-4526(1985). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=K12 / MG1655 / ATCC 47076; RX MEDLINE=97426617; PubMed=9278503; DOI=10.1126/science.277.5331.1453; RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., RA Mau B., Shao Y.; RT "The complete genome sequence of Escherichia coli K-12."; RL Science 277:1453-1474(1997). RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911; RX PubMed=16738553; DOI=10.1038/msb4100049; RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.; RT "Highly accurate genome sequences of Escherichia coli K-12 strains RT MG1655 and W3110."; RL Mol. Syst. Biol. 2:E1-E5(2006). RN [5] RP MASS SPECTROMETRY. RC STRAIN=K12 / ATCC 25404 / DSM 5698 / NCIMB 11290; RX MEDLINE=99196679; PubMed=10094780; DOI=10.1006/abio.1998.3077; RA Arnold R.J., Reilly J.P.; RT "Observation of Escherichia coli ribosomal proteins and their RT posttranslational modifications by mass spectrometry."; RL Anal. Biochem. 269:105-112(1999). RN [6] RP STRUCTURE BY ELECTRON MICROSCOPY (11.50 ANGSTROMS). RC STRAIN=MRE-600; RX MEDLINE=22694394; PubMed=12809609; DOI=10.1016/S0092-8674(03)00427-6; RA Gao H., Sengupta J., Valle M., Korostelev A., Eswar N., Stagg S.M., RA Van Roey P., Agrawal R.K., Harvey S.C., Sali A., Chapman M.S., RA Frank J.; RT "Study of the structural dynamics of the E. coli 70S ribosome using RT real-space refinement."; RL Cell 113:789-801(2003). RN [7] RP X-RAY CRYSTALLOGRAPHY (3.46 ANGSTROMS) OF 2 DIFFERENT RIBOSOME RP STRUCTURES. RC STRAIN=MRE-600; RX PubMed=16272117; DOI=10.1126/science.1117230; RA Schuwirth B.S., Borovinskaya M.A., Hau C.W., Zhang W., RA Vila-Sanjurjo A., Holton J.M., Cate J.H.D.; RT "Structures of the bacterial ribosome at 3.5 A resolution."; RL Science 310:827-834(2005). CC -!- FUNCTION: Binds to a specific region on the 23S rRNA. CC -!- FUNCTION: One of the proteins that surrounds the polypeptide exit CC tunnel on the outside of the subunit. CC -!- SUBUNIT: Part of the 50S ribosomal subunit. CC -!- INTERACTION: CC P0A8Z3:ybgC; NbExp=1; IntAct=EBI-542264, EBI-543276; CC P39336:yjgL; NbExp=1; IntAct=EBI-542264, EBI-549937; CC -!- MASS SPECTROMETRY: MW=11198.0; METHOD=MALDI; RANGE=1-100; CC NOTE=Ref.5. CC -!- SIMILARITY: Belongs to the ribosomal protein L23P family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X02613; CAA26462.1; -; Genomic_DNA. DR EMBL; U18997; AAA58115.1; -; Genomic_DNA. DR EMBL; U00096; AAC76343.1; -; Genomic_DNA. DR EMBL; AP009048; BAE77973.1; -; Genomic_DNA. DR PIR; A65125; R5EC23. DR PDB; 1P85; EM; R=1-100. DR PDB; 1P86; EM; R=1-100. DR PDB; 2AW4; X-ray; T=1-100. DR PDB; 2AWB; X-ray; T=1-100. DR IntAct; P0ADZ0; -. DR ECO2DBASE; I013.0; 6TH EDITION. DR GenomeReviews; U00096_GR; b3318. DR GenomeReviews; AP009048_GR; JW3280. DR KEGG; eco:b3318; -. DR EchoBASE; EB0876; -. DR EcoGene; EG10883; rplW. DR BioCyc; EcoCyc:EG10883-MONOMER; -. DR LinkHub; P0ADZ0; -. DR GO; GO:0005515; F:protein binding; IPI:IntAct. DR InterPro; IPR012677; a_b_plait_nuc_bd. DR InterPro; IPR001014; Ribosomal_L23. DR InterPro; IPR013025; Ribosome_L25_23. DR Pfam; PF00276; Ribosomal_L23; 1. DR ProDom; PD001141; Ribosomal_L23; 1. DR PROSITE; PS00050; RIBOSOMAL_L23; 1. KW 3D-structure; Complete proteome; Direct protein sequencing; KW Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding. FT CHAIN 1 100 50S ribosomal protein L23. FT /FTId=PRO_0000129407. FT CONFLICT 80 80 Missing (in Ref. 1). SQ SEQUENCE 100 AA; 11199 MW; 30CD1D77CC7CF9EB CRC64; MIREERLLKV LRAPHVSEKA STAMEKSNTI VLKVAKDATK AEIKAAVQKL FEVEVEVVNT LVVKGKVKRH GQRIGRRSDW KKAYVTLKEG QNLDFVGGAE //