ID   RL23_ECOLI     STANDARD;      PRT;   100 AA.
AC   P0ADZ0; P02424; Q2M6Y3;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   05-SEP-2006, entry version 10.
DE   50S ribosomal protein L23.
GN   Name=rplW; OrderedLocusNames=b3318;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=K12;
RX   MEDLINE=80092111; PubMed=391594; DOI=10.1016/0014-5793(79)81181-3;
RA   Wittmann-Liebold B., Greuer B.;
RT   "Primary structure of protein L23 from the Escherichia coli
RT   ribosome.";
RL   FEBS Lett. 108:69-74(1979).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=85242118; PubMed=3892488;
RA   Zurawski G., Zurawski S.M.;
RT   "Structure of the Escherichia coli S10 ribosomal protein operon.";
RL   Nucleic Acids Res. 13:4521-4526(1985).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   MEDLINE=97426617; PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J.,
RA   Mau B., Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1474(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains
RT   MG1655 and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   MASS SPECTROMETRY.
RC   STRAIN=K12 / ATCC 25404 / DSM 5698 / NCIMB 11290;
RX   MEDLINE=99196679; PubMed=10094780; DOI=10.1006/abio.1998.3077;
RA   Arnold R.J., Reilly J.P.;
RT   "Observation of Escherichia coli ribosomal proteins and their
RT   posttranslational modifications by mass spectrometry.";
RL   Anal. Biochem. 269:105-112(1999).
RN   [6]
RP   STRUCTURE BY ELECTRON MICROSCOPY (11.50 ANGSTROMS).
RC   STRAIN=MRE-600;
RX   MEDLINE=22694394; PubMed=12809609; DOI=10.1016/S0092-8674(03)00427-6;
RA   Gao H., Sengupta J., Valle M., Korostelev A., Eswar N., Stagg S.M.,
RA   Van Roey P., Agrawal R.K., Harvey S.C., Sali A., Chapman M.S.,
RA   Frank J.;
RT   "Study of the structural dynamics of the E. coli 70S ribosome using
RT   real-space refinement.";
RL   Cell 113:789-801(2003).
RN   [7]
RP   X-RAY CRYSTALLOGRAPHY (3.46 ANGSTROMS) OF 2 DIFFERENT RIBOSOME
RP   STRUCTURES.
RC   STRAIN=MRE-600;
RX   PubMed=16272117; DOI=10.1126/science.1117230;
RA   Schuwirth B.S., Borovinskaya M.A., Hau C.W., Zhang W.,
RA   Vila-Sanjurjo A., Holton J.M., Cate J.H.D.;
RT   "Structures of the bacterial ribosome at 3.5 A resolution.";
RL   Science 310:827-834(2005).
CC   -!- FUNCTION: Binds to a specific region on the 23S rRNA.
CC   -!- FUNCTION: One of the proteins that surrounds the polypeptide exit
CC       tunnel on the outside of the subunit.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit.
CC   -!- MASS SPECTROMETRY: MW=11198.0; METHOD=MALDI; RANGE=1-100;
CC       NOTE=Ref.5.
CC   -!- SIMILARITY: Belongs to the ribosomal protein L23P family.
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DR   EMBL; X02613; CAA26462.1; -; Genomic_DNA.
DR   EMBL; U18997; AAA58115.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76343.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77973.1; -; Genomic_DNA.
DR   PIR; A65125; R5EC23.
DR   PDB; 1P85; EM; R=1-100.
DR   PDB; 1P86; EM; R=1-100.
DR   PDB; 2AW4; X-ray; T=1-100.
DR   PDB; 2AWB; X-ray; T=1-100.
DR   ECO2DBASE; I013.0; 6TH EDITION.
DR   GenomeReviews; U00096_GR; b3318.
DR   EchoBASE; EB0876; -.
DR   EcoGene; EG10883; rplW.
DR   BioCyc; EcoCyc:EG10883-MONOMER; -.
DR   InterPro; IPR012677; a_b_plait_nuc_bd.
DR   InterPro; IPR001014; Ribosomal_L23.
DR   InterPro; IPR013025; Ribosome_L25_23.
DR   Pfam; PF00276; Ribosomal_L23; 1.
DR   ProDom; PD001141; Ribosomal_L23; 1.
DR   PROSITE; PS00050; RIBOSOMAL_L23; 1.
KW   3D-structure; Complete proteome; Direct protein sequencing;
KW   Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding.
FT   CHAIN         1    100       50S ribosomal protein L23.
FT                                /FTId=PRO_0000129407.
FT   CONFLICT     80     80       Missing (in Ref. 1).
SQ   SEQUENCE   100 AA;  11199 MW;  30CD1D77CC7CF9EB CRC64;
     MIREERLLKV LRAPHVSEKA STAMEKSNTI VLKVAKDATK AEIKAAVQKL FEVEVEVVNT
     LVVKGKVKRH GQRIGRRSDW KKAYVTLKEG QNLDFVGGAE
//