ID RL7_SALTY Reviewed; 121 AA. AC P0A299; P18081; DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 2. DT 26-FEB-2008, entry version 24. DE 50S ribosomal protein L7/L12 (L8). GN Name=rplL; OrderedLocusNames=STM4152; ORFNames=STMF1.11; OS Salmonella typhimurium. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Salmonella. OX NCBI_TaxID=602; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=LT2; RX MEDLINE=90356427; PubMed=2201953; RA Zhyvoloup A.N., Woodmaska M.I., Kroupskaya I.V., Paton E.B.; RT "Nucleotide sequence of the rplJL operon and the deduced primary RT structure of the encoded L10 and L7/L12 proteins of Salmonella RT typhimurium compared to that of Escherichia coli."; RL Nucleic Acids Res. 18:4620-4620(1990). RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=LT2; RX MEDLINE=90306303; PubMed=2194828; DOI=10.1016/0014-5793(90)80901-T; RA Paton E.B., Woodmaska M.I., Kroupskaya I.V., Zhyvoloup A.N., RA Matsuka G.K.; RT "Evidence for the ability of L10 ribosomal proteins of Salmonella RT typhimurium and Klebsiella pneumoniae to regulate rplJL gene RT expression in Escherichia coli."; RL FEBS Lett. 265:129-132(1990). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=LT2 / SGSC1412 / ATCC 700720; RX MEDLINE=21534948; PubMed=11677609; DOI=10.1038/35101614; RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E., RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., RA Waterston R., Wilson R.K.; RT "Complete genome sequence of Salmonella enterica serovar Typhimurium RT LT2."; RL Nature 413:852-856(2001). CC -!- FUNCTION: L7/L12 seems to be the binding site for several of the CC factors involved in protein synthesis and appears to be essential CC for accurate translation. CC -!- SUBUNIT: L7/L12 forms dimers with an elongated shape. Two dimers CC associate with a copy of L10 to form a very strong complex (called CC L8). CC -!- PTM: Acetylation of Ser-2 converts L12 to L7 (By similarity). CC -!- SIMILARITY: Belongs to the ribosomal protein L12P family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X53072; CAA37246.1; -; Genomic_DNA. DR EMBL; AF170176; AAF33498.1; -; Genomic_DNA. DR EMBL; AE008894; AAL22980.1; -; Genomic_DNA. DR PIR; S12828; R5EB12. DR RefSeq; NP_463021.1; -. DR HSSP; P02392; 1CTF. DR SMR; P0A299; 2-121. DR GeneID; 1255678; -. DR GenomeReviews; AE006468_GR; STM4152. DR KEGG; stm:STM4152; -. DR StyGene; SG10364; rplL. DR BioCyc; STYP99287:STM4152-MON; -. DR GO; GO:0006412; P:translation; IEA:HAMAP. DR HAMAP; MF_00368; -; 1. DR InterPro; IPR014719; Ribosomal_L7/12_C/ClpS-like. DR InterPro; IPR013823; Ribosomal_L7/L12_C. DR Gene3D; G3DSA:3.30.1390.10; Ribosomal_L7/12_C/ClpS-like; 1. DR Pfam; PF00542; Ribosomal_L12; 1. DR ProDom; PD001326; Ribosomal_L12; 1. PE 3: Inferred from homology; KW Acetylation; Complete proteome; Ribonucleoprotein; Ribosomal protein. FT INIT_MET 1 1 Removed. FT CHAIN 2 121 50S ribosomal protein L7/L12. FT /FTId=PRO_0000157572. FT MOD_RES 2 2 N-acetylserine; in form L7 (By FT similarity). SQ SEQUENCE 121 AA; 12299 MW; 7FE04E5B79802D51 CRC64; MSITKDQIIE AVSAMSVMDV VELISAMEEK FGVSAAAAVA VAAGPAEAAE EKTEFDVILK AAGANKVAVI KAVRGATGLG LKEAKDLVES APAALKEGVS KDDAEALKKS LEEAGAEVEV K //