ID US27_HCMVA STANDARD; PRT; 362 AA. AC P09703; DT 01-MAR-1989 (REL. 10, CREATED) DT 01-MAR-1989 (REL. 10, LAST SEQUENCE UPDATE) DT 01-APR-1993 (REL. 25, LAST ANNOTATION UPDATE) DE G-PROTEIN COUPLED RECEPTOR HOMOLOG US27 (HHRF2). GN US27. OS HUMAN CYTOMEGALOVIRUS (STRAIN AD169). OC VIRIDAE; DS-DNA ENVELOPED VIRUSES; HERPESVIRIDAE; BETAHERPESVIRINAE. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 87169717. RA WESTON K., BARRELL B.G.; RL J. MOL. BIOL. 192:177-208(1986). RN [2] RP COMPLETE GENOME. RX MEDLINE; 90269039. RA CHEE M.S., BANKIER A.T., BECK S., BOHNI R., BROWN C.M., CERNY R., RA HORSNELL T., HUTCHISON C.A. III, KOUZARIDES T., MARTIGNETTI J.A., RA PREDDIE E., SATCHWELL S.C., TOMLINSON P., WESTON K.M., BARRELL B.G.; RL CURR. TOP. MICROBIOL. IMMUNOL. 154:125-169(1990). RN [3] RP SIMILARITY TO G-PROTEIN COUPLED RECEPTORS. RX MEDLINE; 90231415. RA CHEE M.S., SATCHWELL S.C., PREDDIE E., WESTON K.M., BARRELL B.G.; RL NATURE 344:774-777(1990). CC -!- FUNCTION: REGULATION OF HCMV LATENCY OR REACTIVATION \?; POTENTIAL CC PATHWAY FOR VIRALLY TRANSFORMED CELL PROLIFERATION. CC -!- SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. CC -!- SIMILARITY: BELONGS TO FAMILY 1 OF G-PROTEIN COUPLED RECEPTORS. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X17403; G59786; -. DR EMBL; X04650; G59806; -. DR PIR; B27216; QQBED2. DR PIR; S09476; S09476. DR PIR; S09941; S09941. DR GCRDB; GCR_0036; -. DR GCRDB; GCR_0039; -. DR PROSITE; PS00237; G_PROTEIN_RECEPTOR; 1. KW G-PROTEIN COUPLED RECEPTOR; TRANSMEMBRANE; GLYCOPROTEIN. FT DOMAIN 1 34 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 35 58 1 (POTENTIAL). FT DOMAIN 59 67 CYTOPLASMIC (POTENTIAL). FT TRANSMEM 68 90 2 (POTENTIAL). FT DOMAIN 91 104 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 105 126 3 (POTENTIAL). FT DOMAIN 127 148 CYTOPLASMIC (POTENTIAL). FT TRANSMEM 149 167 4 (POTENTIAL). FT DOMAIN 168 193 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 194 213 5 (POTENTIAL). FT DOMAIN 214 233 CYTOPLASMIC (POTENTIAL). FT TRANSMEM 234 257 6 (POTENTIAL). FT DOMAIN 258 274 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 275 298 7 (POTENTIAL). FT DOMAIN 299 362 CYTOPLASMIC (POTENTIAL). FT CARBOHYD 7 7 POTENTIAL. FT CARBOHYD 15 15 POTENTIAL. FT CARBOHYD 18 18 POTENTIAL. FT CARBOHYD 22 22 POTENTIAL. SQ SEQUENCE 362 AA; 41994 MW; 739033B9 CRC32; MTTSTNNQTL TQVSNMTNHT LNSTEIYQLF EYTRLGVWLM CIVGTFLNVL VITTILYYRR KKKSPSDTYI CNLAVADLLI VVGLPFFLEY AKHHPKLSRE VVCSGLNACF YICLFAGVCF LINLSMDRYC VIVWGVELNR VRNNKRATCW VVIFWILAVL MGMPHYLMYS HTNNECVGEF ANETSGWFPV FLNTKVNICG YLAPIALMAY TYNRMVRFII NYVGKWHMQT LHVLLVVVVS FASFWFPFNL ALFLESIRLL AGVYNDTLQN VIIFCLYVGQ FLAYVRACLN PGIYILVGTQ MRKDMWTTLR VFACCCVKQE IPYQDIDIEL QKDIQRRAKH TKRTHYDRKN APMESGEEEF LL //