ID CBP2_WHEAT STANDARD; PRT; 423 AA. AC P08819; DT 01-NOV-1988 (REL. 09, CREATED) DT 01-NOV-1988 (REL. 09, LAST SEQUENCE UPDATE) DT 01-AUG-1991 (REL. 19, LAST ANNOTATION UPDATE) DE SERINE CARBOXYPEPTIDASE II CHAINS A AND B (EC 3.4.16.1). OS TRITICUM AESTIVUM (WHEAT). OC EUKARYOTA; PLANTA; EMBRYOPHYTA; ANGIOSPERMAE; MONOCOTYLEDONEAE; OC CYPERALES; GRAMINEAE. RN [1] RP SEQUENCE. RA BREDDAM K., SORENSEN S.B., SVENDSEN I.; RL CARLSBERG RES. COMMUN. 52:297-311(1987). RN [2] RP X-RAY CRYSTALLOGRAPHY, 3.5 ANGSTROMS. RM 90216664 RA LIAO D.I., REMINGTON S.J.; RL J. BIOL. CHEM. 265:6528-6531(1990). CC -!- CATALYTIC ACTIVITY: PEPTIDYL-L-AMINO ACID + H(2)O = PEPTIDE + CC L-AMINO ACID (THIS ENZYME EXHIBITS A PREFERENCE FOR BASIC AND CC HYDROPHOBIC RESIDUES IN THE P1 AND P1' POSITIONS). CC -!- SUBUNIT: CARBOXYPEPTIDASE II IS A DIMER, WHERE EACH MONOMER IS CC COMPOSED OF TWO CHAINS LINKED BY DISULFIDE BONDS. CC -!- THERE ARE THREE DISULFIDE BONDS IN THE MOLECULE. CC -!- SIMILARITY: TO OTHER SERINE CARBOXYPEPTIDASES. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; A29639; A29639. DR PIR; B29639; B29639. DR PIR; C29639; C29639. DR PDB; 2SC2; 15-APR-91. DR PROSITE; PS00131; CARBOXYPEPTIDASE_SER_SER. DR PROSITE; PS00560; CARBOXYPEPTIDASE_SER_HIS. KW HYDROLASE; CARBOXYPEPTIDASE; GLYCOPROTEIN; ZYMOGEN; 3D-STRUCTURE. FT CHAIN 1 263 SERINE CARBOXYPEPTIDASE II, CHAIN A. FT NON_CONS 263 264 FT CHAIN 264 423 SERINE CARBOXYPEPTIDASE II, CHAIN B. FT ACT_SITE 158 158 FT ACT_SITE 338 338 FT ACT_SITE 392 392 FT CARBOHYD 116 116 FT CARBOHYD 127 127 FT CARBOHYD 259 259 FT CARBOHYD 291 291 FT CARBOHYD 297 297 FT CARBOHYD 421 421 FT VARIANT 1 3 MISSING (IN A' CHAIN). SQ SEQUENCE 423 AA; 47111 MW; 971513 CN; VEPSGHAADR IARLPGQPAV DFDMYSGYIT VDEGAGRSLF YLLQEAPEDA QPAPLVLWLN GGPGCSSVAY GASEELGAFR VKPRGAGLVL NEYRWNKVAN VLFLDSPAGV GFSYTNTSSD IYTSGDNRTA HDSYAFLAKW FERFPHYKYR DFYIAGESYA GHYVPELSQL VHRSKNPVIN LKGFMVGNGL IDDYHDYVGT FEFWWNHGIV SDDTYRRLKE ACLHDSFIHP SPACDAATDV ATAEQGNIDM YSLYTPVCNI TSSTGSYDPC TERYSTAYYN RRDVQMALHA NVTGAMNYTW ATCSDTINTH WHDAPRSMLP IYRELIAAGL RIWVFSGDTD AVVPLTATRY SIGALGLPTT TSWYPWYDDQ EVGGWSQVYK GLTLVSVRGA GHEVPLHRPR QALVLFQYFL QGKPMPGQTK NAT //