ID TKN_KASSE STANDARD; PRT; 12 AA. AC P08611; DT 01-AUG-1988 (Rel. 08, Created) DT 01-AUG-1988 (Rel. 08, Last sequence update) DT 24-JAN-2006 (Rel. 49, Last annotation update) DE Kassinin. OS Kassina senegalensis (Senegal running frog). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Hyperoliidae; OC Kassina. OX NCBI_TaxID=8415; RN [1] RP PROTEIN SEQUENCE. RC TISSUE=Skin secretion; RX MEDLINE=77246385; PubMed=891753; RA Anastasi A., Montecucchi P.C., Erspamer V., Visser J.; RT "Amino acid composition and sequence of kassinin, a tachykinin RT dodecapeptide from the skin of the African frog Kassina RT senegalensis."; RL Experientia 33:857-858(1977). CC -!- FUNCTION: Tachykinins are active peptides which excite neurons, CC evoke behavioral responses, are potent vasodilators and CC secretagogues, and contract (directly or indirectly) many smooth CC muscles. CC -!- SUBCELLULAR LOCATION: Secreted protein. CC -!- TISSUE SPECIFICITY: Expressed by the skin glands. CC -!- SIMILARITY: Belongs to the tachykinin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; S07206; S07206. DR PDB; 1MYU; NMR; A=1-12. DR InterPro; IPR002040; Tachy_Neurokinin. DR Pfam; PF02202; Tachykinin; 1. DR PROSITE; PS00267; TACHYKININ; 1. KW 3D-structure; Amidation; Amphibian defense peptide; KW Direct protein sequencing; Neuropeptide. FT PEPTIDE 1 12 Kassinin. FT /FTId=PRO_0000044397. FT MOD_RES 12 12 Methionine amide. SQ SEQUENCE 12 AA; 1336 MW; 91757AB89DD6DAB5 CRC64; DVPKSDQFVG LM //