ID   IFNA5_MOUSE    STANDARD;      PRT;   189 AA.
AC   P07349;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1988, sequence version 1.
DT   18-APR-2006, entry version 50.
DE   Interferon alpha-5 precursor.
GN   Name=Ifna5;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=85215516; PubMed=2987811;
RA   Kelly K.A., Pitha P.M.;
RT   "Characterization of a mouse interferon gene locus I. Isolation of a
RT   cluster of four alpha interferon genes.";
RL   Nucleic Acids Res. 13:805-823(1985).
CC   -!- FUNCTION: Produced by macrophages, IFN-alpha have antiviral
CC       activities. Interferon stimulates the production of two enzymes: a
CC       protein kinase and an oligoadenylate synthetase.
CC   -!- SUBCELLULAR LOCATION: Secreted protein.
CC   -!- SIMILARITY: Belongs to the alpha/beta interferon family.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X01971; CAA26003.1; ALT_SEQ; Genomic_DNA.
DR   PIR; C23087; IVMSA5.
DR   UniGene; Mm.377089; -.
DR   HSSP; P01563; 1ITF.
DR   MGI; MGI:107663; Ifna5.
DR   InterPro; IPR009079; 4_helix_cytokine.
DR   InterPro; IPR000471; Interferon_abd.
DR   PANTHER; PTHR11691; Interferon_abd; 1.
DR   Pfam; PF00143; Interferon; 1.
DR   PRINTS; PR00266; INTERFERONAB.
DR   ProDom; PD000550; Interferon_abd; 1.
DR   SMART; SM00076; IFabd; 1.
DR   PROSITE; PS00252; INTERFERON_A_B_D; 1.
KW   Antiviral defense; Cytokine; Glycoprotein; Signal.
FT   SIGNAL        1     23
FT   CHAIN        24    189       Interferon alpha-5.
FT                                /FTId=PRO_0000016378.
FT   CARBOHYD    101    101       N-linked (GlcNAc...) (Probable).
FT   DISULFID     24    122       By similarity.
FT   DISULFID     52    162       By similarity.
SQ   SEQUENCE   189 AA;  21514 MW;  8BB9CDFD15F5C3BD CRC64;
     MARLCAFLMV LPVLSYWPTC SLGCDLPQTH NLRNKRALTL LVKMRRLSPL SCLKDRKDFG
     FPQEKVGAQQ IQEAQAIPVL SELTQQVLNI FTSKDSSAAW NATLLDSFCN EVHQQLNDLK
     ACVMQQVGVQ ESPLTQEDSL LAVRKYFHRI TVYLREKKHS PCAWEVVRAE VWRALSSSVN
     LLARLSKEE
//