ID PRZN$SERSP STANDARD; PRT; 486 AA. AC P07268; DT 01-APR-1988 (REL. 07, CREATED) DT 01-APR-1988 (REL. 07, LAST SEQUENCE UPDATE) DT 01-MAR-1989 (REL. 10, LAST ANNOTATION UPDATE) DE EXTRACELLULAR METALLOPROTEINASE PRECURSOR (EC 3.4.24.-) (ZINC DE PROTEINASE). OS SERRATIA SP. (E-15). OC PROKARYOTA; BACTERIA; GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS; OC ENTEROBACTERIACEAE. RN [1] (SEQUENCE FROM N.A.) RA NAKAHAMA K., YOSHIMURA K., MARUMOTO R., KIKUCHI M., LEE I.S., RA HASE T., MATSUBARA H.; RL NUCLEIC ACIDS RES. 14:5843-5855(1986). RN [2] (SEQUENCE OF 17-34 AND 179-269) RA LEE I.S., WAKABAYASHI S., MIYATA K., TOMODA K., YONEDA M., KANGAWA K., RA MINAMINO N., MATSUO H., MATSUBARA H.; RL J. BIOCHEM. 96:1409-1418(1984). CC -!- REQUIRES A ZINC ATOM, WHICH IS ESSENTIAL FOR PROTEOLYTIC ACTIVITY. CC -!- SIMILARITY: WITH THERMOLYSIN. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X04127; SSPROT. KW HYDROLASE; ZINC; METALLOPROTEASE; SIGNAL. FT SIGNAL 1 16 FT CHAIN 17 486 METALLOPROTEINASE. FT METAL 192 192 CATALYTIC ZINC (BY HOMOLOGY). FT ACT_SITE 193 193 BY HOMOLOGY. FT METAL 196 196 CATALYTIC ZINC (BY HOMOLOGY). FT METAL 245 245 CATALYTIC ZINC (BY HOMOLOGY). SQ SEQUENCE 486 AA; 52406 MW; 1147390 CN; MQSTKKAIEI TESNFAAATT GYDAVDDLLH YHERGNGIQI NGKDSFSNEQ AGLFITRENQ TWNGYKVFGQ PVKLTFSFPD YKFSSTNVAG DTGLSKFSAE QQQQAKLSLQ SWADVANITF TEVAAGQKAN ITFGNYSQDR PGHYDYGTQA YAFLPNTIWQ GQDLGGQTWY NVNQSNVKHP ATEDYGRQTF THEIGHALGL SHPGDYNAGE GNPTYRDVTY AEDTRQFSLM SYWSETNTGG DNGGHYAAAP LLDDIAAIQH LYGANLSTRT GDTVYGFNSN TGRDFLSTTS NSQKVIFAAW DAGGNDTFDF SGYTANQRIN LNEKSFSDVG GLKGNVSIAA GVTIENAIGF RQRLIVGNAA NNVLKGGAGN DVLFGGGGAD ELWGGAGKDI FVFSAASDSA PGASDWIRDF QKGIDKIDLS FFNKEAQSSD FIHFVDHFSG AAGEALLSYN ASNNVTDLSV NIGGHQAPDF LVKIVGQVDV ATDFIV //