ID TBA2$MOUSE STANDARD; PRT; 451 AA. AC P05213; DT 01-AUG-1988 (ANNOTATIONS EDITED) DT 13-AUG-1987 (TRANSLATED FROM AN EMBL ENTRY) DE TUBULIN ALPHA CHAIN ISOTYPE M-ALPHA-2. OS MOUSE (MUS MUSCULUS). OC EUKARYOTA. RN [1] (SEQUENCE FROM N.A.) RA VILLASANTE A., WANG D., DOBNER P., DOLPH P., LEWIS S.A., COWAN N.J.; RL MOL. CELL. BIOL. 6:2409-2419(1986). CC -!- FUNCTION: TUBULIN IS THE MAJOR CONSTITUENT OF MICROTUBULES. IT CC BINDS TWO MOLES OF GTP, ONE AT AN EXCHANGEABLE SITE ON THE BETA CC CHAIN AND ONE AT A NONEXCHANGEABLE SITE ON THE ALPHA-CHAIN. CC -!- SUBUNIT: DIMER OF ALPHA AND BETA CHAINS. CC -!- M-ALPHA-2 IS UBIQUITOUSLY EXPRESSED. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M13446; MMTUBA2M. KW MICROTUBULES; GTP-BINDING; MULTIGENE FAMILY. FT NP_BIND 142 148 GTP (PUTATIVE). FT SITE 451 451 INVOLVED IN POLYMERIZATION. SQ SEQUENCE 451 AA; 50165 MW; 1033116 CN; MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK HVPRAVFVDL EPTVIDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI GKEIIDLVLD RIRKLADQCT GLQGFLVFHS FGGGTGSGFT SLLMERLSVD YGKKSKLEFS IYPAPQVSTA VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL ISQIVSSITA SLRFDGALNV DLTEFQTNLV PYPRIHFPLA TYAPVISAEK AYHEQLSVAE ITNACFEPAN QMVKCDPRHG KYMACCLLYR GDVVPKDVNA AIATIKTKRT IQFVDWCPTG FKVGINYQPP TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE AREDMAALEK DYEEVGVDSV EGEGEEEGEE Y //