ID PHEA_MICDP Reviewed; 164 AA. AC P05098; DT 13-AUG-1987, integrated into UniProtKB/Swiss-Prot. DT 13-AUG-1987, sequence version 1. DT 22-FEB-2023, entry version 102. DE RecName: Full=C-phycoerythrin alpha chain; GN Name=cpeA; OS Microchaete diplosiphon (Fremyella diplosiphon). OC Bacteria; Cyanobacteria; Nostocales; Rivulariaceae; Microchaete. OX NCBI_TaxID=1197; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX PubMed=2431391; DOI=10.1093/nar/14.21.8279; RA Mazel D., Guglielmi G., Houmard J., Sidler W., Bryant D.A., RA Tandeau de Marsac N.; RT "Green light induces transcription of the phycoerythrin operon in the RT cyanobacterium Calothrix 7601."; RL Nucleic Acids Res. 14:8279-8290(1986). RN [2] RP PROTEIN SEQUENCE, AND CHROMOPHORE BINDING AT CYS-82 AND CYS-139. RX PubMed=3092842; DOI=10.1515/bchm3.1986.367.2.627; RA Sidler W., Kumpf B., Ruediger W., Zuber H.; RT "The complete amino-acid sequence of C-phycoerythrin from the RT cyanobacterium Fremyella diplosiphon."; RL Biol. Chem. Hoppe-Seyler 367:627-642(1986). CC -!- FUNCTION: Light-harvesting photosynthetic bile pigment-protein from the CC phycobiliprotein complex. CC -!- SUBUNIT: Heterodimer of an alpha and a beta chain. CC -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane; Peripheral membrane CC protein; Cytoplasmic side. Note=Forms the periphery of the CC phycobilisome rod. CC -!- INDUCTION: By green light but not by red light. CC -!- PTM: Contains two covalently linked bilin chromophores. CC -!- SIMILARITY: Belongs to the phycobiliprotein family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X04592; CAA28261.1; -; Genomic_DNA. DR AlphaFoldDB; P05098; -. DR SMR; P05098; -. DR GO; GO:0030089; C:phycobilisome; IEA:UniProtKB-KW. DR GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell. DR GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. DR Gene3D; 1.10.490.20; Phycocyanins; 1. DR InterPro; IPR009050; Globin-like_sf. DR InterPro; IPR012128; Phycobilisome_asu/bsu. DR InterPro; IPR038719; Phycobilisome_asu/bsu_sf. DR PANTHER; PTHR34011:SF4; C-PHYCOCYANIN ALPHA SUBUNIT; 1. DR PANTHER; PTHR34011; PHYCOBILISOME 32.1 KDA LINKER POLYPEPTIDE, PHYCOCYANIN-ASSOCIATED, ROD 2-RELATED; 1. DR Pfam; PF00502; Phycobilisome; 1. DR PIRSF; PIRSF000081; Phycocyanin; 1. DR SUPFAM; SSF46458; Globin-like; 1. PE 1: Evidence at protein level; KW Antenna complex; Bile pigment; Chromophore; Direct protein sequencing; KW Electron transport; Membrane; Photosynthesis; Phycobilisome; Thylakoid; KW Transport. FT CHAIN 1..164 FT /note="C-phycoerythrin alpha chain" FT /id="PRO_0000199173" FT BINDING 82 FT /ligand="(2R,3E)-phycoerythrobilin" FT /ligand_id="ChEBI:CHEBI:85276" FT /ligand_label="1" FT /note="covalent" FT BINDING 139 FT /ligand="(2R,3E)-phycoerythrobilin" FT /ligand_id="ChEBI:CHEBI:85276" FT /ligand_label="2" FT /note="covalent" SQ SEQUENCE 164 AA; 17626 MW; 80C0F3F5010DB9C1 CRC64; MKSVVTTVIA AADAAGRFPS TSDLESVQGS IQRAAARLEA AEKLANNIDA VATEAYNACI KKYPYLNNSG EANSTDTFKA KCARDIKHYL RLIQYSLVVG GTGPLDEWGI AGQREVYRAL GLPTAPYVEA LSFARNRGCA PRDMSAQALT EYNALLDYAI NSLS //