ID UR2A_CYPCA STANDARD; PRT; 125 AA. AC P04560; DT 13-AUG-1987 (Rel. 05, Created) DT 01-JAN-1988 (Rel. 06, Last sequence update) DT 01-OCT-2000 (Rel. 40, Last annotation update) DE UII ALPHA PRECURSOR [CONTAINS: UROPHYSIN ALPHA; UROTENSIN II-ALPHA]. OS Cyprinus carpio (Common carp). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Euteleostei; Ostariophysi; OC Cypriniformes; Cyprinidae; Cyprininae; Cyprinus. OX NCBI_TaxID=7962; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=86307061; PubMed=2427672; RA Ohsako S., Ishida I., Ichikawa T., Deguchi T.; RT "Cloning and sequence analysis of cDNAs encoding precursors of RT urotensin II-alpha and -gamma."; RL J. Neurosci. 6:2730-2735(1986). RN [2] RP SEQUENCE OF 114-125. RA Munekata E., Ohtaki T., Ichikawa T., McMaster D., Lederis K.; RL (In) Rich D.H., Gross E. (eds.); RL Proceedings of the 7th american peptide symposium, pp.69-72, RL Pierce Chemical Co., Rockford Il. (1981). CC -!- FUNCTION: UROTENSIN IS FOUND IN THE TELEOST CAUDAL NEUROSECRETORY CC SYSTEM. IT HAS A SUGGESTED ROLE IN OSMOREGULATION AND AS A CC CORTICOTROPIN-RELEASING FACTOR. THE NONHORMONAL PORTION OF THIS CC PRECURSOR MAY BE A UROTENSIN BINDING PROTEIN, UROPHYSIN. CC -!- SIMILARITY: BELONGS TO THE UROTENSIN 2 FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M14084; AAA49215.1; -. DR InterPro; IPR001483; Urotensin_II. DR Pfam; PF02083; Urotensin_II; 1. DR PROSITE; PS00984; UROTENSIN_II; 1. KW Hormone; Cleavage on pair of basic residues; Signal. FT SIGNAL 1 21 FT CHAIN 22 106 UROPHYSIN ALPHA (POTENTIAL). FT PEPTIDE 114 125 UROTENSIN II-ALPHA. FT DISULFID 119 124 SQ SEQUENCE 125 AA; 13840 MW; 1FB6F86CA6B3A5AF CRC64; MMCNLLLSFS VLLLSCTHLV AHPVTDTADM TYSGPDSVEE AGGVSPDDFA VSDLNDLLQR AAVVEYSPLL SRENIKVPGQ IPKEALRELL LEKPYRLIPP SGLWGSRRQF RKRGGGADCF WKYCV //