ID UR2A_CYPCA STANDARD; PRT; 125 AA. AC P04560; DT 13-AUG-1987 (Rel. 05, Created) DT 01-JAN-1988 (Rel. 06, Last sequence update) DT 15-DEC-1998 (Rel. 37, Last annotation update) DE UROTENSIN II, ALPHA PRECURSOR. OS Cyprinus carpio (Common carp). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Actinopterygii; OC Neopterygii; Teleostei; Euteleostei; Ostariophysi; Cypriniformes; OC Cyprinoidea; Cyprinidae; Cyprininae; Cyprinus. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 86307061. RA OHSAKO S., ISHIDA I., ICHIKAWA T., DEGUCHI T.; RT "Cloning and sequence analysis of cDNAs encoding precursors of RT urotensin II-alpha and -gamma."; RL J. Neurosci. 6:2730-2735(1986). RN [2] RP SEQUENCE OF 114-125. RA MUNEKATA E., OHTAKI T., ICHIKAWA T., MCMASTER D., LEDERIS K.; RL (In) Rich D.H., Gross E. (eds.); RL Proceedings of the 7th american peptide symposium, pp.69-72, RL Pierce Chemical Co., Rockford Il. (1981). CC -!- FUNCTION: UROTENSIN IS FOUND IN THE TELEOST CAUDAL NEUROSECRETORY CC SYSTEM. IT HAS A SUGGESTED ROLE IN OSMOREGULATION AND AS A CC CORTICOTROPIN-RELEASING FACTOR. THE NONHORMONAL PORTION OF THIS CC PRECURSOR MAY BE A UROTENSIN BINDING PROTEIN, UROPHYSIN. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M14084; AAA49215.1; -. DR PROSITE; PS00984; UROTENSIN_II; 1. KW Hormone; Cleavage on pair of basic residues; Signal. FT SIGNAL 1 21 FT CHAIN 22 106 UROPHYSIN (POTENTIAL). FT PEPTIDE 114 125 UROTENSIN II-ALPHA. FT DISULFID 119 124 SQ SEQUENCE 125 AA; 13840 MW; 9FBF65A2 CRC32; MMCNLLLSFS VLLLSCTHLV AHPVTDTADM TYSGPDSVEE AGGVSPDDFA VSDLNDLLQR AAVVEYSPLL SRENIKVPGQ IPKEALRELL LEKPYRLIPP SGLWGSRRQF RKRGGGADCF WKYCV //