ID UR2A_CYPCA STANDARD; PRT; 125 AA. AC P04560; DT 13-AUG-1987 (REL. 05, CREATED) DT 01-JAN-1988 (REL. 06, LAST SEQUENCE UPDATE) DT 15-DEC-1998 (REL. 37, LAST ANNOTATION UPDATE) DE UROTENSIN II, ALPHA PRECURSOR. OS CYPRINUS CARPIO (COMMON CARP). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; ACTINOPTERYGII; NEOPTERYGII; OC TELEOSTEI; EUTELEOSTEI; OSTARIOPHYSI; CYPRINIFORMES; CYPRINOIDEA; OC CYPRINIDAE; CYPRININAE; CYPRINUS. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 86307061. RA OHSAKO S., ISHIDA I., ICHIKAWA T., DEGUCHI T.; RT "Cloning and sequence analysis of cDNAs encoding precursors of RT urotensin II-alpha and -gamma."; RL J. NEUROSCI. 6:2730-2735(1986). RN [2] RP SEQUENCE OF 114-125. RA MUNEKATA E., OHTAKI T., ICHIKAWA T., MCMASTER D., LEDERIS K.; RL (IN) RICH D.H., GROSS E. (EDS.); RL PROCEEDINGS OF THE 7TH AMERICAN PEPTIDE SYMPOSIUM, PP.69-72, RL PIERCE CHEMICAL CO., ROCKFORD IL. (1981). CC -!- FUNCTION: UROTENSIN IS FOUND IN THE TELEOST CAUDAL NEUROSECRETORY CC SYSTEM. IT HAS A SUGGESTED ROLE IN OSMOREGULATION AND AS A CC CORTICOTROPIN-RELEASING FACTOR. THE NONHORMONAL PORTION OF THIS CC PRECURSOR MAY BE A UROTENSIN BINDING PROTEIN, UROPHYSIN. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M14084; G213067; -. DR PROSITE; PS00984; UROTENSIN_II; 1. KW HORMONE; CLEAVAGE ON PAIR OF BASIC RESIDUES; SIGNAL. FT SIGNAL 1 21 FT CHAIN 22 106 UROPHYSIN (POTENTIAL). FT PEPTIDE 114 125 UROTENSIN II-ALPHA. FT DISULFID 119 124 SQ SEQUENCE 125 AA; 13840 MW; 9FBF65A2 CRC32; MMCNLLLSFS VLLLSCTHLV AHPVTDTADM TYSGPDSVEE AGGVSPDDFA VSDLNDLLQR AAVVEYSPLL SRENIKVPGQ IPKEALRELL LEKPYRLIPP SGLWGSRRQF RKRGGGADCF WKYCV //