ID MERP_SHIFL STANDARD; PRT; 91 AA. AC P04129; P07042; DT 01-NOV-1986 (REL. 03, CREATED) DT 01-NOV-1986 (REL. 03, LAST SEQUENCE UPDATE) DT 01-NOV-1997 (REL. 35, LAST ANNOTATION UPDATE) DE MERCURIC TRANSPORT PROTEIN PERIPLASMIC COMPONENT PRECURSOR DE (PERIPLASMIC MERCURY ION BINDING PROTEIN) (MERCURY SCAVENGER PROTEIN). GN MERP. OS SHIGELLA FLEXNERI. OG PLASMID NR1 (R100). OC PROKARYOTA; GRACILICUTES; SCOTOBACTERIA; FACULTATIVELY ANAEROBIC RODS; OC ENTEROBACTERIACEAE. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 85014891. RA MISRA T.K., BROWN N.L., FRITZINGER D.C., PRIDMORE R.D., BARNES W.M., RA HABERSTROH L., SILVER S.; RL PROC. NATL. ACAD. SCI. U.S.A. 81:5975-5979(1984). RN [2] RP SEQUENCE FROM N.A. RC TRANSPOSON=TN21; RX MEDLINE; 85159407. RA BARRINEAU P., GILBERT P., JACKSON W.J., JONES C.S., SUMMERS A.O., RA WISDOM S.; RL J. MOL. APPL. GENET. 2:601-619(1984). RN [3] RP STRUCTURE BY NMR. RX MEDLINE; 97332449. RA STEELE R.A., OPELLA S.J.; RL BIOCHEMISTRY 36:6885-6895(1997). CC -!- FUNCTION: MERCURY SCAVENGER THAT SPECIFICALLY BINDS TO ONE HG(2+) CC ION AND WHICH PASSES IT TO THE MERCURIC REDUCTASE (MERA) VIA THE CC MERT PROTEIN. CC -!- SUBUNIT: MONOMER. CC -!- SUBCELLULAR LOCATION: PERIPLASMIC (PROBABLE). CC -!- SIMILARITY: CONTAINS A COPY OF THE HEAVY-METAL-ASSOCIATED (HMA) CC DOMAIN. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; J01730; G151751; -. DR EMBL; K03089; G150394; -. DR PIR; A03556; RGEBHD. DR PDB; 1AFI; 23-JUL-97. DR PDB; 1AFJ; 23-JUL-97. DR PROSITE; PS01047; HMA; 1. KW TRANSPORT; MERCURIC RESISTANCE; PERIPLASMIC; METAL-BINDING; SIGNAL; KW TRANSPOSABLE ELEMENT; PLASMID; 3D-STRUCTURE. FT SIGNAL 1 19 POTENTIAL. FT CHAIN 20 91 MERCURIC TRANSPORT PERIPLASMIC COMPONENT. FT DOMAIN 28 57 HMA. FT METAL 33 33 HG(2+) (POTENTIAL). FT METAL 36 36 HG(2+) (POTENTIAL). FT CONFLICT 51 51 S -> T (IN REF. 2). SQ SEQUENCE 91 AA; 9414 MW; 70C4CF5F CRC32; MKKLFASLAL AAAVAPVWAA TQTVTLAVPG MTCAACPITV KKALSKVEGV SKVDVGFEKR EAVVTFDDTK ASVQKLTKAT ADAGYPSSVK Q //