ID HBB_DASNO STANDARD; PRT; 146 AA. AC P02087; Q45XI0; DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot. DT 25-OCT-2005, sequence version 2. DT 27-JUN-2006, entry version 45. DE Hemoglobin subunit beta (Hemoglobin beta chain) (Beta-globin). GN Name=HBB; OS Dasypus novemcinctus (Nine-banded armadillo). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Xenarthra; Dasypodidae; Dasypus. OX NCBI_TaxID=9361; RN [1] RP PROTEIN SEQUENCE. RX MEDLINE=81208315; PubMed=7236709; DOI=10.1016/0005-2795(81)90148-3; RA de Jong W.W., Leunissen J.A.M., Cuijpers H.T.; RT "Primary structure of the major beta-chain of armadillo (Dasypus RT novemcinctus) haemoglobin."; RL Biochim. Biophys. Acta 668:57-62(1981). RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RA Sloan A.M., Campbell K.L.; RT "Atypical molecular evolution of afrotherian and xenarthran beta- RT globin cluster genes."; RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Involved in oxygen transport from the lung to the CC various peripheral tissues. CC -!- SUBUNIT: Heterotetramer of two alpha chains and two beta chains. CC -!- TISSUE SPECIFICITY: Red blood cells. CC -!- SIMILARITY: Belongs to the globin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DQ091213; AAZ22684.1; -; Genomic_DNA. DR PIR; A02403; HBDN. DR HSSP; P02023; 1UIW. DR SMR; P02087; 1-146. DR InterPro; IPR002337; Beta_haem. DR InterPro; IPR000971; Globin. DR InterPro; IPR012292; Globin_related. DR Pfam; PF00042; Globin; 1. DR PRINTS; PR00814; BETAHAEM. DR PROSITE; PS01033; GLOBIN; 1. KW Direct protein sequencing; Heme; Iron; Metal-binding; KW Oxygen transport; Transport. FT INIT_MET 0 0 FT CHAIN 1 146 Hemoglobin subunit beta. FT /FTId=PRO_0000052945. FT METAL 63 63 Iron (heme distal ligand). FT METAL 92 92 Iron (heme proximal ligand). FT CONFLICT 23 23 C -> H (in Ref. 1). FT CONFLICT 104 104 K -> R (in Ref. 1). FT CONFLICT 114 114 L -> M (in Ref. 1). FT CONFLICT 124 125 WH -> HW (in Ref. 1). FT CONFLICT 132 132 K -> R (in Ref. 1). SQ SEQUENCE 146 AA; 16220 MW; 984B9B1E0FD71898 CRC64; VNLTSDEKTA VLALWNKVDV EDCGGEALGR LLVVYPWTQR FFESFGDLST PAAVFANAKV KAHGKKVLTS FGEGMNHLDN LKGTFAKLSE LHCDKLHVDP ENFKLLGNML VVVLARHFGK EFDWHMHACF QKVVAGVANA LAHKYH //