ID HBA_SAPAP Reviewed; 142 AA. AC P01928; DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 2. DT 16-SEP-2015, entry version 81. DE RecName: Full=Hemoglobin subunit alpha; DE AltName: Full=Alpha-globin; DE AltName: Full=Hemoglobin alpha chain; GN Name=HBA; OS Sapajus apella (Brown-capped capuchin) (Cebus apella). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Platyrrhini; Cebidae; Cebinae; Sapajus. OX NCBI_TaxID=9515; RN [1] RP PROTEIN SEQUENCE OF 2-142. RX PubMed=4215719; RA Matsuda G., Maita T., Watanabe B., Araya A., Morokuma K., Ota Y., RA Goodman M., Barnabas J., Prychodko W.; RT "The amino acid sequences of the alpha and beta polypeptide chains of RT adult hemoglobin of the capuchin monkey (Cebus apella)."; RL Hoppe-Seyler's Z. Physiol. Chem. 354:1513-1516(1973). CC -!- FUNCTION: Involved in oxygen transport from the lung to the CC various peripheral tissues. CC -!- SUBUNIT: Heterotetramer of two alpha chains and two beta chains. CC -!- TISSUE SPECIFICITY: Red blood cells. CC -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE- CC ProRule:PRU00238}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; A02254; HAMQA. DR PRIDE; P01928; -. DR HOVERGEN; HBG009709; -. DR GO; GO:0005833; C:hemoglobin complex; IEA:InterPro. DR GO; GO:0020037; F:heme binding; IEA:InterPro. DR GO; GO:0005506; F:iron ion binding; IEA:InterPro. DR GO; GO:0019825; F:oxygen binding; IEA:InterPro. DR GO; GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. DR Gene3D; 1.10.490.10; -; 1. DR InterPro; IPR000971; Globin. DR InterPro; IPR009050; Globin-like. DR InterPro; IPR012292; Globin/Proto. DR InterPro; IPR002338; Haemoglobin_a. DR InterPro; IPR002339; Haemoglobin_pi. DR Pfam; PF00042; Globin; 1. DR PRINTS; PR00612; ALPHAHAEM. DR PRINTS; PR00815; PIHAEM. DR SUPFAM; SSF46458; SSF46458; 1. DR PROSITE; PS01033; GLOBIN; 1. PE 1: Evidence at protein level; KW Acetylation; Direct protein sequencing; Heme; Iron; Metal-binding; KW Oxygen transport; Phosphoprotein; Transport. FT INIT_MET 1 1 Removed. {ECO:0000250|UniProtKB:P18969}. FT CHAIN 2 142 Hemoglobin subunit alpha. FT /FTId=PRO_0000052592. FT METAL 59 59 Iron (heme distal ligand). FT METAL 88 88 Iron (heme proximal ligand). FT MOD_RES 4 4 Phosphoserine. FT {ECO:0000250|UniProtKB:P69905}. FT MOD_RES 8 8 N6-succinyllysine. FT {ECO:0000250|UniProtKB:P01942}. FT MOD_RES 9 9 Phosphothreonine. FT {ECO:0000250|UniProtKB:P69905}. FT MOD_RES 12 12 N6-succinyllysine. FT {ECO:0000250|UniProtKB:P01942}. FT MOD_RES 17 17 N6-acetyllysine; alternate. FT {ECO:0000250|UniProtKB:P69905}. FT MOD_RES 17 17 N6-succinyllysine; alternate. FT {ECO:0000250|UniProtKB:P01942}. FT MOD_RES 25 25 Phosphotyrosine. FT {ECO:0000250|UniProtKB:P69905}. FT MOD_RES 36 36 Phosphoserine. FT {ECO:0000250|UniProtKB:P69905}. FT MOD_RES 41 41 N6-succinyllysine. FT {ECO:0000250|UniProtKB:P01942}. FT MOD_RES 50 50 Phosphoserine. FT {ECO:0000250|UniProtKB:P69905}. SQ SEQUENCE 142 AA; 15255 MW; 404C5216FF7D22AE CRC64; MVLSPADKTN VKTAWGKVGG HAGDYGAEAL ERMFLSFPTT KTYFPHFDLS HGSAQVKGHG KKVADALSNA VAHVDDMPNA LSALSDLHAH KLRVDPVNFK LLSHCLLVTL AAHHPADFTP AVHASLDKFL ASVSTVLTSK YR //