ID   HBA_CHLAE               Reviewed;         142 AA.
AC   P01926;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   07-SEP-2016, entry version 88.
DE   RecName: Full=Hemoglobin subunit alpha;
DE   AltName: Full=Alpha-globin;
DE   AltName: Full=Hemoglobin alpha chain;
GN   Name=HBA;
OS   Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus.
OX   NCBI_TaxID=9534;
RN   [1]
RP   PROTEIN SEQUENCE OF 2-142.
RX   PubMed=4214754;
RA   Matsuda G., Maita T., Watanabe B., Araya A., Morokuma K., Goodman M.,
RA   Prychodko W.;
RT   "The amino acid sequences of the alpha and beta polypeptide chains of
RT   adult hemoglobin of the savannah monkey (Cereopithecus aethiops).";
RL   Hoppe-Seyler's Z. Physiol. Chem. 354:1153-1155(1973).
CC   -!- FUNCTION: Involved in oxygen transport from the lung to the
CC       various peripheral tissues.
CC   -!- SUBUNIT: Heterotetramer of two alpha chains and two beta chains.
CC   -!- TISSUE SPECIFICITY: Red blood cells.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   PIR; A02252; HAMQC.
DR   ProteinModelPortal; P01926; -.
DR   SMR; P01926; 1-142.
DR   HOVERGEN; HBG009709; -.
DR   GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
DR   CDD; cd08927; Hb-alpha_like; 1.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR002338; Haemoglobin_a-typ.
DR   InterPro; IPR002339; Haemoglobin_pi.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00612; ALPHAHAEM.
DR   PRINTS; PR00815; PIHAEM.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Direct protein sequencing; Heme; Iron; Metal-binding;
KW   Oxygen transport; Phosphoprotein; Transport.
FT   INIT_MET      1      1       Removed. {ECO:0000250|UniProtKB:P18969}.
FT   CHAIN         2    142       Hemoglobin subunit alpha.
FT                                /FTId=PRO_0000052594.
FT   METAL        59     59       Iron (heme distal ligand).
FT   METAL        88     88       Iron (heme proximal ligand).
FT   MOD_RES       4      4       Phosphoserine.
FT                                {ECO:0000250|UniProtKB:P69905}.
FT   MOD_RES       8      8       N6-succinyllysine.
FT                                {ECO:0000250|UniProtKB:P01942}.
FT   MOD_RES      12     12       N6-succinyllysine.
FT                                {ECO:0000250|UniProtKB:P01942}.
FT   MOD_RES      17     17       N6-acetyllysine; alternate.
FT                                {ECO:0000250|UniProtKB:P69905}.
FT   MOD_RES      17     17       N6-succinyllysine; alternate.
FT                                {ECO:0000250|UniProtKB:P01942}.
FT   MOD_RES      25     25       Phosphotyrosine.
FT                                {ECO:0000250|UniProtKB:P69905}.
FT   MOD_RES      36     36       Phosphoserine.
FT                                {ECO:0000250|UniProtKB:P69905}.
FT   MOD_RES      41     41       N6-succinyllysine.
FT                                {ECO:0000250|UniProtKB:P01942}.
FT   MOD_RES      50     50       Phosphoserine.
FT                                {ECO:0000250|UniProtKB:P69905}.
FT   MOD_RES     103    103       Phosphoserine.
FT                                {ECO:0000250|UniProtKB:P01942}.
FT   MOD_RES     109    109       Phosphothreonine.
FT                                {ECO:0000250|UniProtKB:P01942}.
FT   MOD_RES     125    125       Phosphoserine.
FT                                {ECO:0000250|UniProtKB:P01942}.
FT   MOD_RES     132    132       Phosphoserine.
FT                                {ECO:0000250|UniProtKB:P01942}.
FT   MOD_RES     135    135       Phosphothreonine.
FT                                {ECO:0000250|UniProtKB:P01942}.
FT   MOD_RES     138    138       Phosphothreonine.
FT                                {ECO:0000250|UniProtKB:P01942}.
FT   MOD_RES     139    139       Phosphoserine.
FT                                {ECO:0000250|UniProtKB:P01942}.
SQ   SEQUENCE   142 AA;  15238 MW;  E0E4217128B1FF09 CRC64;
     MVLSPADKSN VKAAWGKVGG HAGEYGAEAL ERMFLSFPTT KTYFPHFDLS HGSAQVKGHG
     KKVADALTLA VGHVDDMPHA LSALSDLHAH KLRVDPVNFK LLSHCLLVTL AAHLPAEFTP
     AVHASLDKFL ASVSTVLTSK YR
//