ID GC1M_MOUSE STANDARD; PRT; 393 AA. AC P01869; DT 21-JUL-1986 (REL. 01, CREATED) DT 01-AUG-1991 (REL. 19, LAST SEQUENCE UPDATE) DT 01-AUG-1991 (REL. 19, LAST ANNOTATION UPDATE) DE IG GAMMA-1 CHAIN C REGION, MEMBRANE-BOUND FORM. OS MUS MUSCULUS (MOUSE). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA; OC EUTHERIA; RODENTIA. RN [1] RP SEQUENCE FROM N.A. RM 80045036 RA HONJO T., OBATA M., YAMAWAKI-KATAOKA Y., KATAOKA T., KAWAKAMI T., RA TAKAHASHI N., MANO Y.; RL CELL 18:559-568(1979). RN [2] RP SEQUENCE OF 323-393 FROM N.A. RM 82197626 RA TYLER B.M., COWMAN A.F., GERONDAKIS S.D., ADAMS J.M., BERNARD O.; RL PROC. NATL. ACAD. SCI. U.S.A. 79:2008-2012(1982). RN [3] RP SEQUENCE OF 323-366 FROM N.A. RM 82115295 RA ROGERS J., CHOI E., SOUZA L., CARTER C., WORD C.J., KUEHL M., RA EISENBERG D., WALL R.; RL CELL 26:19-27(1981). RN [4] RP SEQUENCE OF 1-44 FROM N.A. RM 82222190 RA YAMAWAKI-KATAOKA Y., NAKAI S., MIYATA T., HONJO T.; RL PROC. NATL. ACAD. SCI. U.S.A. 79:2623-2627(1982). CC -!- ALTERNATIVE PRODUCTS: CELL LINES PRODUCING IGG CONTAIN TWO MRNA CC SPECIES FOR IG GAMMA CHAINS. THE MAJOR SPECIES ENCODES SECRETED CC GAMMA CHAINS. A LESS ABUNDANT SPECIES APPEARS TO ENCODE MEMBRANE- CC BOUND CHAINS IN THAT IT CONTAINS AN ALTERNATIVE 3' END, ENCODED CC IN SEPARATE EXONS, THAT IS HOMOLOGOUS WITH THE MEMBRANE-BOUND CC SEGMENT OF MU CHAINS. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; V00793; MMIGG1. DR PIR; B02159; G1MSM. DR PROSITE; PS00290; IG_MHC. KW IMMUNOGLOBULIN C REGION; ALTERNATIVE SPLICING; TRANSMEMBRANE; KW GLYCOPROTEIN. FT NON_TER 1 1 FT DOMAIN 1 97 CH1. FT DOMAIN 98 110 HINGE. FT DOMAIN 111 217 CH2. FT DOMAIN 218 324 CH3. FT DISULFID 27 82 FT DISULFID 102 102 INTERCHAIN (WITH A HEAVY CHAIN). FT DISULFID 104 104 INTERCHAIN (WITH A HEAVY CHAIN). FT DISULFID 107 107 INTERCHAIN (WITH A HEAVY CHAIN). FT DISULFID 109 109 INTERCHAIN (WITH A HEAVY CHAIN). FT DISULFID 138 198 FT CARBOHYD 174 174 FT DISULFID 244 302 FT TRANSMEM 340 357 POTENTIAL. FT DOMAIN 358 393 CYTOPLASMIC (POTENTIAL). SQ SEQUENCE 393 AA; 43386 MW; 885119 CN; AKTTPPSVYP LAPGSAAQTN SMVTLGCLVK GYFPEPVTVT WNSGSLSSGV HTFPAVLQSD LYTLSSSVTV PSSPRPSETV TCNVAHPASS TKVDKKIVPR DCGCKPCICT VPEVSSVFIF PPKPKDVLTI TLTPKVTCVV VDISKDDPEV QFSWFVDDVE VHTAQTQPRE EQFNSTFRSV SELPIMHQDW LNGKEFKCRV NSAAFPAPIE KTISKTKGRP KAPQVYTIPP PKEQMAKDKV SLTCMITDFF PEDITVEWQW NGQPAENYKN TQPIMNTNGS YFVYSKLNVQ KSNWEAGNTF TCSVLHEGLH NHHTEKSLSH SPGLQLDETC AEAQDGELDG LWTTITIFIS LFLLSVCYSA AVTLFKVKWI FSSVVELKQT LVPEYKNMIG QAP //