ID IBP_CARCR Reviewed; 110 AA. AC P00993; DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot. DT 21-JUL-1986, sequence version 1. DT 10-AUG-2010, entry version 62. DE RecName: Full=Chelonianin; DE AltName: Full=Basic protease inhibitor; DE AltName: Full=RTPI; OS Caretta caretta (Loggerhead sea turtle). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Testudines; Cryptodira; Chelonioidea; Cheloniidae; Caretta. OX NCBI_TaxID=8467; RN [1] RP PROTEIN SEQUENCE. RC TISSUE=Egg white; RA Kato I., Tominaga N.; RT "Trypsin-subtilisin inhibitor from red sea turtle eggwhite consists of RT two tandem domains -- one Kunitz -- one of a new family."; RL Fed. Proc. 38:832-832(1979). CC -!- FUNCTION: The first domain inhibits trypsin; the second one CC inhibitis subtilisin. CC -!- SIMILARITY: Contains 1 BPTI/Kunitz inhibitor domain. CC -!- SIMILARITY: Contains 1 WAP domain. CC -!- CAUTION: As the paper only indicates the species as "red sea CC turtle", the species indicated here is therefore an inference. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; A01224; TITTOR. DR ProteinModelPortal; P00993; -. DR SMR; P00993; 4-83. DR MEROPS; I02.022; -. DR MEROPS; I17.004; -. DR GO; GO:0005576; C:extracellular region; IEA:InterPro. DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW. DR InterPro; IPR015874; 4-disulphide_core. DR InterPro; IPR002223; Prot_inh_Kunz-m. DR InterPro; IPR020901; Prtase_inh_Kunz-CS. DR InterPro; IPR008197; Whey_acidic_protein_4-diS_core. DR Gene3D; G3DSA:4.10.410.10; Prot_inh_Kunz-m; 1. DR Pfam; PF00014; Kunitz_BPTI; 1. DR Pfam; PF00095; WAP; 1. DR PRINTS; PR00003; 4DISULPHCORE. DR PRINTS; PR00759; BASICPTASE. DR SMART; SM00131; KU; 1. DR SMART; SM00217; WAP; 1. DR SUPFAM; SSF57362; Prot_inh_Kunz-m; 1. DR SUPFAM; SSF57256; WAP; 1. DR PROSITE; PS00280; BPTI_KUNITZ_1; 1. DR PROSITE; PS50279; BPTI_KUNITZ_2; 1. DR PROSITE; PS51390; WAP; 1. PE 1: Evidence at protein level; KW Direct protein sequencing; Disulfide bond; Protease inhibitor; KW Pyrrolidone carboxylic acid; Serine protease inhibitor. FT CHAIN 1 110 Chelonianin. FT /FTId=PRO_0000155409. FT DOMAIN 8 58 BPTI/Kunitz inhibitor. FT DOMAIN 60 105 WAP. FT SITE 18 19 Reactive bond for trypsin. FT MOD_RES 1 1 Pyrrolidone carboxylic acid. FT DISULFID 8 58 By similarity. FT DISULFID 17 41 By similarity. FT DISULFID 33 54 By similarity. FT DISULFID 67 92 By similarity. FT DISULFID 76 97 By similarity. FT DISULFID 80 93 By similarity. FT DISULFID 86 101 By similarity. SQ SEQUENCE 110 AA; 11916 MW; 269436243813418E CRC64; QGDKRDICRL PPEQGPCKGR IPRYFYNPAS RMCESFIYGG CKGNKNNFKT KAECVRACRP PERPGVCPKT SGPGICLHGC DSDSDCKEGQ KCCFDGCGYI CLTVAPSGSP //