ID IBP_CARCR STANDARD; PRT; 110 AA. AC P00993; DT 21-JUL-1986 (Rel. 01, Created) DT 21-JUL-1986 (Rel. 01, Last sequence update) DT 15-DEC-1998 (Rel. 37, Last annotation update) DE CHELONIANIN (BASIC PROTEASE INHIBITOR) (RTPI). OS Caretta caretta (Loggerhead). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Testudines; OC Cryptodira; Chelonioidea; Cheloniidae; Caretta. RN [1] RP SEQUENCE. RC TISSUE=EGG WHITE; RA KATO I., TOMINAGA N.; RT "Trypsin-subtilisin inhibitor from red sea turtle eggwhite consists RT of two tandem domains -- one Kunitz -- one of a new family."; RL Fed. Proc. 38:832-832(1979). CC -!- MISCELLANEOUS: THIS INHIBITOR, ISOLATED FROM EGG WHITE, CONSISTS CC OF TWO NONHOMOLOGOUS DOMAINS. CC -!- SIMILARITY: THE FIRST DOMAIN BELONGS TO THE BPTI/KUNITZ FAMILY OF CC INHIBITORS. CC -!- SIMILARITY: THE SECOND DOMAIN IS A WAP-TYPE 'FOUR-DISULFIDE CORE' CC DOMAIN. CC -!- CAUTION: AS THE PAPER ONLY INDICATES THE SPECIES AS "RED SEA CC TURTLE", THE SPECIES INDICATED HERE IS THEREFORE AN INFERENCE. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; A01224; TITTOR. DR HSSP; P00974; 1BRB. DR PFAM; PF00014; Kunitz_BPTI; 1. DR PFAM; PF00095; wap; 1. DR PROSITE; PS00280; BPTI_KUNITZ; 1. DR PROSITE; PS00317; 4_DISULFIDE_CORE; 1. KW Serine protease inhibitor. FT DOMAIN 1 58 INHIBIT TRYPSIN. FT DOMAIN 59 110 INHIBIT SUBTILISIN. FT MOD_RES 1 1 PYRROLIDONE CARBOXYLIC ACID. FT ACT_SITE 18 19 REACTIVE BOND (TRYPSIN). SQ SEQUENCE 110 AA; 11916 MW; 728E92BB CRC32; QGDKRDICRL PPEQGPCKGR IPRYFYNPAS RMCESFIYGG CKGNKNNFKT KAECVRACRP PERPGVCPKT SGPGICLHGC DSDSDCKEGQ KCCFDGCGYI CLTVAPSGSP //