ID ATP6_MOUSE STANDARD; PRT; 226 AA. AC P00848; DT 21-JUL-1986 (REL. 01, CREATED) DT 21-JUL-1986 (REL. 01, LAST SEQUENCE UPDATE) DT 15-DEC-1998 (REL. 37, LAST ANNOTATION UPDATE) DE ATP SYNTHASE A CHAIN (EC 3.6.1.34) (PROTEIN 6). GN MTATP6 OR MT-ATP6 OR ATP6 OR ATPASE6. OS MUS MUSCULUS (MOUSE). OG MITOCHONDRION. OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; MAMMALIA; EUTHERIA; OC RODENTIA; SCIUROGNATHI; MURIDAE; MURINAE; MUS. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 82137051. RA BIBB M.J., VAN ETTEN R.A., WRIGHT C.T., WALBERG M.W., CLAYTON D.A.; RT "Sequence and gene organization of mouse mitochondrial DNA."; RL CELL 26:167-180(1981). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=BALB/C; RA SATO M., MATSUKI Y., OGUMA T., TADAKUMA T.; RL SUBMITTED (SEP-1998) TO EMBL/GENBANK/DDBJ DATA BANKS. CC -!- FUNCTION: KEY COMPONENT OF THE PROTON CHANNEL; IT MAY PLAY A CC DIRECT ROLE IN THE TRANSLOCATION OF PROTONS ACROSS THE MEMBRANE. CC -!- SUBUNIT: F-TYPE ATPASES HAVE 2 COMPONENTS, CF(1) - THE CATALYTIC CC CORE - AND CF(0) - THE MEMBRANE PROTON CHANNEL. CF(1) HAS FIVE CC SUBUNITS: ALPHA(3), BETA(3), GAMMA(1), DELTA(1), EPSILON(1). CF(0) CC HAS THREE MAIN SUBUNITS: A, B AND C. CC -!- SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. CC -!- SIMILARITY: BELONGS TO THE ATPASE A CHAIN FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; J01420; G342523; -. DR EMBL; V00711; G13844; -. DR EMBL; AF093677; G3719449; -. DR PIR; A01051; PWMS6. DR MGD; MGI:99927; MT-ATP6. DR PROSITE; PS00449; ATPASE_A; 1. DR PFAM; PF00119; ATP-synt_A; 1. KW HYDROGEN ION TRANSPORT; CF(0); MITOCHONDRION; TRANSMEMBRANE. SQ SEQUENCE 226 AA; 25095 MW; AC703707 CRC32; MNENLFASFI TPTMMGFPIV VAIIMFPSIL FPSSKRLINN RLHSFQHWLV KLIIKQMMLI HTPKGRTWTL MIVSLIMFIG STNLLGLLPH TFTPTTQLSM NLSMAIPLWA GAVITGFRHK LKSSLAHFLP QGTPISLIPM LIIIETISLF IQPMALAVRL TANITAGHLL MHLIGGATLV LMNISPPTAT ITFIILLLLT ILEFAVALIQ AYVFTLLVSL YLHDNT //