ID ATP6_MOUSE STANDARD; PRT; 226 AA. AC P00848; DT 21-JUL-1986 (REL. 01, CREATED) DT 21-JUL-1986 (REL. 01, LAST SEQUENCE UPDATE) DT 01-OCT-1994 (REL. 30, LAST ANNOTATION UPDATE) DE ATP SYNTHASE A CHAIN (EC 3.6.1.34) (PROTEIN 6). OS MUS MUSCULUS (MOUSE). OG MITOCHONDRION. OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA; OC EUTHERIA; RODENTIA. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 82137051. RA BIBB M.J., VAN ETTEN R.A., WRIGHT C.T., WALBERG M.W., CLAYTON D.A.; RL CELL 26:167-180(1981). CC -!- FUNCTION: KEY COMPONENT OF THE PROTON CHANNEL; IT MAY PLAY A CC DIRECT ROLE IN THE TRANSLOCATION OF PROTONS ACROSS THE MEMBRANE. CC -!- SUBUNIT: F-TYPE ATPASES HAVE 2 COMPONENTS, CF(1) - THE CATALYTIC CC CORE - AND CF(0) - THE MEMBRANE PROTON CHANNEL. CF(1) HAS FIVE CC SUBUNITS: ALPHA(3), BETA(3), GAMMA(1), DELTA(1), EPSILON(1). CF(0) CC HAS THREE MAIN SUBUNITS: A, B AND C. CC -!- SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. CC -!- SIMILARITY: BELONGS TO THE ATPASE A CHAIN FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; J01420; J01420. DR EMBL; V00711; V00711. DR PIR; A01051; PWMS6. DR PROSITE; PS00449; ATPASE_A. KW HYDROGEN ION TRANSPORT; CF(0); MITOCHONDRION; TRANSMEMBRANE. SQ SEQUENCE 226 AA; 25095 MW; 287807 CN; MNENLFASFI TPTMMGFPIV VAIIMFPSIL FPSSKRLINN RLHSFQHWLV KLIIKQMMLI HTPKGRTWTL MIVSLIMFIG STNLLGLLPH TFTPTTQLSM NLSMAIPLWA GAVITGFRHK LKSSLAHFLP QGTPISLIPM LIIIETISLF IQPMALAVRL TANITAGHLL MHLIGGATLV LMNISPPTAT ITFIILLLLT ILEFAVALIQ AYVFTLLVSL YLHDNT //