ID O96784_MACRS Unreviewed; 74 AA. AC O96784; DT 01-MAY-1999, integrated into UniProtKB/TrEMBL. DT 01-MAY-1999, sequence version 1. DT 29-MAY-2024, entry version 58. DE SubName: Full=Crustacean Hyperglycemic Hormone (CHH) {ECO:0000313|EMBL:CAA10269.1}; DE Flags: Fragment; GN Name=CHH {ECO:0000313|EMBL:CAA10269.1}; OS Macrobrachium rosenbergii (Giant fresh water prawn). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea; OC Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Caridea; OC Palaemonoidea; Palaemonidae; Macrobrachium. OX NCBI_TaxID=79674 {ECO:0000313|EMBL:CAA10269.1}; RN [1] {ECO:0000313|EMBL:CAA10269.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=10048184; DOI=10.1016/S1095-6433(98)10139-3; RA Lin C.Y., Chen S.H., Kou G.H., Kuo C.M.; RT "Identification and characterization of a hyperglycemic hormone from RT freshwater giant prawn, Macrobrachium rosenbergii."; RL Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 121:315-321(1998). RN [2] {ECO:0000313|EMBL:CAA10269.1} RP NUCLEOTIDE SEQUENCE. RA Chung-Yen L., Shu-Hwa C., Guang-Hsiung K., Ching-Ming K.; RL Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. CC -!- SIMILARITY: Belongs to the arthropod CHH/MIH/GIH/VIH hormone family. CC {ECO:0000256|ARBA:ARBA00005447}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ130968; CAA10269.1; -; mRNA. DR AlphaFoldDB; O96784; -. DR SMR; O96784; -. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro. DR GO; GO:0007623; P:circadian rhythm; IEA:TreeGrafter. DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW. DR Gene3D; 1.10.2010.10; Crustacean CHH/MIH/GIH neurohormone; 1. DR InterPro; IPR018251; Crust_neurhormone_CS. DR InterPro; IPR031098; Crust_neurohorm. DR InterPro; IPR035957; Crust_neurohorm_sf. DR InterPro; IPR001166; Hyperglycemic. DR InterPro; IPR000346; Hyperglycemic1. DR PANTHER; PTHR35981; ION TRANSPORT PEPTIDE, ISOFORM C; 1. DR PANTHER; PTHR35981:SF2; ION TRANSPORT PEPTIDE, ISOFORM C; 1. DR Pfam; PF01147; Crust_neurohorm; 1. DR PRINTS; PR00548; HYPRGLYCEMC1. DR PRINTS; PR00550; HYPRGLYCEMIC. DR SUPFAM; SSF81778; Crustacean CHH/MIH/GIH neurohormone; 1. DR PROSITE; PS01250; CHH_MIH_GIH; 1. PE 2: Evidence at transcript level; KW Amidation {ECO:0000256|ARBA:ARBA00022815}; KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, KW ECO:0000256|PIRSR:PIRSR631098-51}; Hormone {ECO:0000256|ARBA:ARBA00022702}; KW Neuropeptide {ECO:0000256|ARBA:ARBA00023320}; KW Secreted {ECO:0000256|ARBA:ARBA00022525}. FT DISULFID 7..43 FT /evidence="ECO:0000256|PIRSR:PIRSR631098-51" FT DISULFID 23..39 FT /evidence="ECO:0000256|PIRSR:PIRSR631098-51" FT DISULFID 26..52 FT /evidence="ECO:0000256|PIRSR:PIRSR631098-51" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:CAA10269.1" FT NON_TER 74 FT /evidence="ECO:0000313|EMBL:CAA10269.1" SQ SEQUENCE 74 AA; 8716 MW; D4DDE3822B1EE9BF CRC64; AILDQSCKGI FDRELFKKLD RVCDDCYNLY RKPYVAIDCR EGCYQNLVFR QCIQDLQLMD QLDEYANAVQ IVGK //